The cover features a snapshot from a molecular dynamics simulation of an ionic fluid mixture. The four spherical particle species, shown here, exhibit strong asymmetry in their hard-core diameters and electric charges. The diameters of the small red and blue particles are exaggerated by a factor of 15 in the figures. The obtained results can be used to extract colloidal effective interaction potentials, including nonsaturated effective charge numbers, at a high-numerical efficiency. The method described by Marco Heinen, Elshad Allahyarov, and Hartmut Löwen on page 275 could be augmented to include colloidal surface chemistry in future projects.