Research Article

You have free access to this content

Application of Electrochemical Biosensors in Clinical Diagnosis

  1. Rastislav Monošík1,*,
  2. Miroslav Stred'anský2,
  3. Ernest Šturdík1

Article first published online: 24 JAN 2012

DOI: 10.1002/jcla.20500

Issue

Journal of Clinical Laboratory Analysis

Journal of Clinical Laboratory Analysis

Volume 26, Issue 1, pages 22–34, January 2012

Additional Information

How to Cite

Monošík, R., Stred'anský, M. and Šturdík, E. (2012), Application of Electrochemical Biosensors in Clinical Diagnosis. J. Clin. Lab. Anal., 26: 22–34. doi: 10.1002/jcla.20500

Author Information

  1. 1

    Institute of Biochemistry, Nutrition and Health Protection, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovak Republic

  2. 2

    Biorealis Ltd., Bratislava, Slovak Republic

*Correspondence to: Rastislav Monošík, Institute of Biochemistry, Nutrition and Health Protection, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinskeho 9, 812 37 Bratislava, Slovak Republic.

Publication History

  1. Issue published online: 24 JAN 2012
  2. Article first published online: 24 JAN 2012
  3. Manuscript Accepted: 8 SEP 2011
  4. Manuscript Received: 1 JUN 2011

Funded by

  • Slovak Research and Development Agency. Grant Number: VMSP-P-0073-09
  • Agency of the Ministry of Education, Science, Research and Sport of the Slovak Republic for the Structural Funds. Grant Number: ITMS 26240220040

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (622K)

Keywords:

  • amperometric;
  • analysis;
  • biosensor;
  • clinical diagnosis;
  • enzyme

Analyses in the clinical area need quick and reliable analytical methods and devices. For this purpose, biosensors can be a suitable option, whereas they are constructed to be simple for use, specific for the target analyte, capable of continuous monitoring and giving quick results, potentially low-costing and portable. In this article, we describe electrochemical biosensors developed for clinical diagnosis, namely for glucose, lactate, cholesterol, urea, creatinine, DNA, antigens, antibodies, and cancer markers assays. Chosen biosensors showed desirable sensitivity, selectivity, and potential for application on real samples. They are often designed to avoid interference with undesired components present in the monitored systems.

View Full Article (HTML) Get PDF (622K)