Salivary cortisol levels and the cortisol response to dexamethasone before and after EMDR: A case report
Article first published online: 26 NOV 2002
Copyright © 2002 Wiley Periodicals, Inc.
Journal of Clinical Psychology
Volume 58, Issue 12, pages 1521–1530, December 2002
How to Cite
Heber, R., Kellner, M. and Yehuda, R. (2002), Salivary cortisol levels and the cortisol response to dexamethasone before and after EMDR: A case report. J. Clin. Psychol., 58: 1521–1530. doi: 10.1002/jclp.10102
- Issue published online: 26 NOV 2002
- Article first published online: 26 NOV 2002
- NIMH. Grant Numbers: RO1 49536, RO1 49555
- Deutsche Forschungsgemeinschaft. Grant Number: DFG, Ke-595/2–1
Trauma survivors with posttraumatic stress disorder (PTSD) have been shown to have lower basal cortisol levels in the urine, plasma, and saliva than in trauma survivors without PTSD, nontraumatized mentally ill, or healthy subjects. We report on a case study in which we measured pre- and post-Eye Movement Desensitization and Reprocessing (EMDR) treatment salivary cortisol levels and salivary cortisol response to 0.50 mg of dexamethasone in a 41-year-old female with chronic PTSD symptoms. Our goal was to determine whether symptom improvement following trauma-focused treatment (EMDR) is associated with changes in basal salivary cortisol or in the cortisol response to dexamethasone administration. Our findings show moderate symptom improvement, an increase in basal cortisol levels, and a more attenuated cortisol hypersuppression in response to the dexamethasone suppression test following EMDR treatment. These results suggest the potential utility of including neuroendocrine measures in the assessment of treatment outcome in PTSD. © 2002 Wiley Periodicals, Inc. J Clin Psychol 58: 1521–1530, 2002.