Attention deficit hyperactivity disorder (ADHD) in adults is increasingly recognized as a common disorder that can significantly impact workplace functioning, yet few clinicians or career consultants have training in how to help adults select careers or jobs within a chosen career that are a good match for their strengths, weaknesses, ADHD tendencies, and coexisting conditions. Straightforward career counseling is inadequate to meet the needs of adults who have ADHD, and significant follow-up, brain-based counseling or therapy is often necessary to help these adults implement the recommendations generated by an ADHD career assessment. This article guides the clinician through the multiple steps of clinical interview, assessment, and intervention when working with adults who have ADHD who face challenges in the workplace. © 2005 Wiley Periodicals, Inc. J Clin Psychol/In Session 61: 549–563, 2005.