Ancient DNA as a multidisciplinary experience
Article first published online: 14 JUN 2004
Copyright © 2004 Wiley-Liss, Inc.
Journal of Cellular Physiology
Volume 202, Issue 2, pages 315–322, February 2005
How to Cite
Cipollaro, M., Galderisi, U. and Di Bernardo, G. (2005), Ancient DNA as a multidisciplinary experience. J. Cell. Physiol., 202: 315–322. doi: 10.1002/jcp.20116
- Issue published online: 23 NOV 2004
- Article first published online: 14 JUN 2004
- Manuscript Accepted: 23 MAR 2004
- Manuscript Received: 17 MAR 2004
Investigation into DNA from archeological remains offers an inestimable tool for unraveling the history of humankind. However, a series of basic and technical difficulties renders the analysis of ancient DNA (aDNA) molecules troublesome, depending either on their own peculiar characteristics or on the complexity of processes affecting the bone matrix over time, all compromising the preservation of ancient DNA. This review underlines the contribution of many different disciplines, in particular molecular biology and genetics, to overcome these obstacles. The role of each expertise is illustrated to appropriately address the questions arising in aDNA investigations. © 2004 Wiley-Liss, Inc.