SWI/SNF: The crossroads where extracellular signaling pathways meet chromatin
Article first published online: 9 SEP 2005
Copyright © 2005 Wiley-Liss, Inc.
Journal of Cellular Physiology
Volume 207, Issue 2, pages 309–314, May 2006
How to Cite
Simone, C. (2006), SWI/SNF: The crossroads where extracellular signaling pathways meet chromatin. J. Cell. Physiol., 207: 309–314. doi: 10.1002/jcp.20514
- Issue published online: 24 FEB 2006
- Article first published online: 9 SEP 2005
- Manuscript Accepted: 28 JUL 2005
- Manuscript Received: 27 JUL 2005
The coordinated expression of the genome in response to extracellular cues is ensured by enzymatic cascades signaling to the nucleus. These pathways generate chromatin modifications at specific loci controlling the transcription of signal-dependent and tissue-specific genes. The SWI/SNF chromatin remodeling complex offers the ideal surface for integrating these signals in the execution of diverse or even opposite biological programs. J. Cell. Physiol. 207: 309–314, 2006. © 2005 Wiley-Liss, Inc.