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LITERATURE CITED

  • Arnott J, Nuglozeh E, Safadi FF, Popoff SN. 2006. TGF-β acts a downstream mediator of extracellular matrix production in osteoblasts. J Cell Physiol (in press).
  • Aronow MA, Gerstenfeld LC, Owen TA, Tassinari MS, Stein GS, Lian JB. 1990. Factors that promote progressive of the osteoblast phenotype in cultured fetal rat calvaria cells. J Cell Physiol 143: 213221.
  • Balemans W, Van Hul W. 2002. Extracellular regulation of BMP signaling in vertebrates: a cocktail of Modulators. Dev Biol 250: 231250.
  • Bandari PS, Qian J, Yehia G, Joshi DD, Maloof PB, Potian J, Oh HS, Gascon P, Harrison JS, Rameshwar P. 2003. Hematopoietic growth factor inducible neurokinin-1 type: a transmembrane protein that is similar to neurokinin 1 interacts with substance P. Regul Pept 111: 169178.
  • Berson JF, Harper DC, Tenza D, Raposo G, Marks MS. 2001. Pmel17 initiates premelanosome morphogenesis within multivesicular bodies. Mol Biol Cell 11: 34513464.
  • Bonnelye E, Merdad L, Kung V, Aubin JE. 2001. The orphan nuclear estrogen receptor-related receptor alpha (ERRalpha) is expressed throughout osteoblast differentiation and regulates bone formation in vitro. J Cell Biol 153: 971984.
  • Eimon PM, Harland RM. 1999. In Xenopus embryos, BMP heterodimers are not required for Mesoderm induction, but BMP activity is necessary for dorsal/ventral patterning. Dev Biol 216: 2940.
  • Galindo M, Pratap J, Young DW, Hovhannisyan H, Im HJ, Choi JY, Lian JB, Stein JL, Stein GS, van Wijnen AJ. 2005. The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts. J Biol Chem 280: 2027420285.
  • Gersbach CA, Byers BA, Pavlath GK, Garcia AJ. 2004. Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. Exp Cell Res 300: 406417.
  • Gori F, Demay MB. 2005. The effects of BIG-3 on osteoblast differentiation are not dependent upon endogenously produced BMPs. Exp Cell Res 304: 287292.
  • Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Belmonte JC, Choe S. 2002. Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature 420: 636642.
  • Hata A, Lagna G, Massague J, Hemmati-Brivanlou A. 1998. Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Genes Dev 12: 186197.
  • Hay E, Hott M, Graulet AM, Lomri A, Marie PJ. 1999. Effects of bone morphogenetic protein-2 on human neonatal calvaria cell differentiation. J Cell Biochem 72: 8193.
  • Imamura T, Takase M, Nishihara A, Oeda E, Hanai J-I, Kawabata M, Miyazono K. 1997. Smad6 inhibits signaling by the TGF-β superfamily. Nature 389: 622626.
  • Karsenty G, Wagner EF. 2002. Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2: 389406.
  • Katagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T, Rosen V, Wozney JM, Fujisawa-Sehara A, Suda T. 1994. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 127: 17551766.
  • Kavsak P, Rasmussen RK, Causing CG, Bonni S, Zhu H, Thomsen GH, Wrana JL. 2000. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. Mol Cell 6: 13651375.
  • Kawai S, Faucheu C, Gallea S, Spinella-Jaegle S, Atfi A, Baron R, Roman SR. 2000. Mouse smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity. Biochem Biophys Res Commun 271: 682687.
  • Kingsley DM. 1994. The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in differentorganisms. Genes Dev 8: 133146.
  • Kretzschmar M, Liu F, Hata A, Doody J, Massague J. 1997. The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Genes Dev 11: 984995.
  • Lechleider RJ, Ryan JL, Garrett L, Eng C, Deng C, Wynshaw-Boris A, Roberts AB. 2001. Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion. Dev Biol 240: 157167.
  • Liu Z, Shi W, Ji X, Sun C, Jee WS, Wu Y, Mao Z, Nagy TR, Li Q, Cao X. 2004. Molecules mimicking Smad1 interacting with Hox stimulate bone formation. J Biol Chem 279: 1131311319.
  • Loging WT, Lal A, Siu IM, Loney TL, Wikstrand CJ, Marra MA, Prange C, Bigner DD, Strausberg RL, Riggins GJ. 2000. Identifying potential tumor markers and antigens by database mining and rapid expression screening. Genome Res 10: 13931402.
  • Lopez-Rovira T, Chalaux E, Massague J, Rosa JL, Ventura F. 2002. Direct binding of Smad1 and Smad4 to two distinct motifs mediates bone morphogenetic protein-specific transcriptional activation of Id1 gene. J Biol Chem 277: 31763185.
  • Metz RL, Yehia G, Fernandes H, Donnelly RJ, Rameshwar P. 2005. Cloning and characterization of the 5′ flanking region of the HGFIN gene indicate a cooperative role among p53 and cytokine-mediated transcription factors: relevance to cell cycle regulation. Cell Cycle 2: 315322.
  • Miyazono K, ten Dijke P, Heldin CH. 2000. TGF-β signaling by Smad proteins. Adv Immunol 75: 115157.
  • Nakao A, Afrakhte M, Moren A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P. 1997. Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signaling. Nature 389: 631635.
  • Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B. 2002. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108: 1729.
  • Onaga M, Ido A, Hasuike S, Uto H, Moriuchi A, Nagata K, Hori T, Hayash K, Tsubouchi H. 2003. Osteoactivin expressed during cirrhosis development in rats fed a choline-deficient, l-amino acid-defined diet, accelerates motility of hepatoma cells. J Hepatol 39: 779785.
  • Qi W, Twigg S, Chen X, Polhill TS, Poronnik P, Gilbert RE, Pollock CA. 2005. Integrated actions of transforming growth factor-beta1 and connective tissue growth factor in renal fibrosis. Am J Physiol Renal Physiol 288: F800F809.
  • Rawadi G, Vayssiere B, Dunn F, Baron R, Roman-Roman S. 2003. BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop. J Bone Miner Res 10: 18421853.
  • Reddi AH. 1994. Bone and cartilage differentiation. Curr Opin Genet Dev 4: 737744.
  • Rich JN, Shi Q, Hjelmeland M, Cummings TJ, Kuan CT, Bigner DD, Counter CM, Wang XF. 2003. Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. J Biol Chem 278: 1595115957.
  • Safadi FF, Xu J, Smock SL, Rico MC, Owen TA, Popoff SN. 2002. Cloning and characterisation of osteoactivin, a novel cDNA expressed in osteoblasts. J Cell Biochem 84: 1226.
  • Safadi FF, Xu J, Smock SL, Kanaan RA, Selim AH, Odgren PR, Marks SC Jr, Owen TA, Popoff SN. 2003. Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo. J Cell Physiol 196: 5162.
  • Selim AA, Abdelmagid SM, Kanaan RA, Smock SL, Owen TA, Popoff SN, Safadi FF. 2003. Anti- osteoactivin antibody inhibits osteoblast differentiation and function in vitro. Crit Rev Eukaryot Gene Expr 13: 265275.
  • Shikano S, Bonkobara M, Zukas PK, Ariizumi K. 2001. Molecular cloning of dendritic cell- associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulphate proteoglycans. J Biol Chem 276: 81258134.
  • Souchelnytskyi S, Nakayama T, Nakao A, Moren A, Heldin CH, Christian JL, ten Dijke P. 1998. Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-beta receptors. J Biol Chem 273: 2536425370.
  • Sykaras N, Opperman LA. 2003. Bone morphogenetic proteins (BMPs): how do they function and what can they offer the clinician?. J Oral Sci 45: 5773.
  • Tremblay KD, Dunn NR, Robertson EJ. 2001. Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. Development 128: 36093621.
  • Urist MR. 1965. Bone: Formation by autoinduction. Science 150: 893899.
  • Wang EA, Israel DI, Kelly S, Luxenberg DP. 1993. Bone morphogenetic protein-2 causes commitment and differentiation in C3Hl0T1/2 and 3T3 cells. Growth Factors 9: 5771.
  • Wetermann MA, Ajubin N, van Dinter IM, Degen WG, van Muijen GN, Ruiter DJ. 1995. Nmb, a novel gene, is expressed in low-metastatic human melanoma cell lines and xenografts. Int J Cancer 60: 7381.
  • Wozney JM. 1998. The bone morphogenetic protein family: Multifunctional cellular regulators in the embryo and adult. Eur J Oral Sci 106: 160166.
  • Yang X, Ji X, Shi X, Cao X. 2000. Smad1 domains interacting with Hoxc-8 induce osteoblast Differentiation. J Biol Chem 275: 10651072.
  • Zhang H, Bradley A. 1996b. Mice deficient for BMP2 are non-viable and have defects in amnion/chorion and cardiac development. Development 122: 29772986.
  • Zhang Y, Chang C, Gehling DJ, Hemmati-Brivanlou A, Derynck R. 2001. Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase. Proc Natl Acad Sci USA 98: 974979.
  • Zhou H, Hammonds R Jr, Findlay DM, Martin TJ, Ng KW. 1993. Differential effects of transforming growth factor-beta 1 and bone morphogenetic protein 4 on gene expression and differentiated function of preosteoblasts. J Cell Physiol 155: 112119.
  • Zhu H, Kavsak P, Abdollah S, Wrana JL, Thomsen GH. 1999. A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature 400: 687693.