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Original Research Article

Enhanced lipid—but not carbohydrate—supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice

  1. Joris Hoeks1,*,
  2. Zolt Arany2,
  3. Esther Phielix1,
  4. Esther Moonen-Kornips1,
  5. Matthijs K.C. Hesselink3,
  6. Patrick Schrauwen1

Article first published online: 22 DEC 2011

DOI: 10.1002/jcp.22812

Issue

Journal of Cellular Physiology

Journal of Cellular Physiology

Volume 227, Issue 3, pages 1026–1033, March 2012

Additional Information

How to Cite

Hoeks, J., Arany, Z., Phielix, E., Moonen-Kornips, E., Hesselink, M. K.C. and Schrauwen, P. (2012), Enhanced lipid—but not carbohydrate—supported mitochondrial respiration in skeletal muscle of PGC-1α overexpressing mice. J. Cell. Physiol., 227: 1026–1033. doi: 10.1002/jcp.22812

Author Information

  1. 1

    NUTRIM—School for Nutrition, Toxicology and Metabolism, Department of Human Biology, Maastricht University Medical Center, Maastricht, The Netherlands

  2. 2

    Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts

  3. 3

    NUTRIM—School for Nutrition, Toxicology and Metabolism, Department of Human Movement Sciences, Maastricht University Medical Center, Maastricht, The Netherlands

*NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center, Department of Human Biology, P.O. Box 616, 6200 MD Maastricht, The Netherlands.

Publication History

  1. Issue published online: 22 DEC 2011
  2. Article first published online: 22 DEC 2011
  3. Accepted manuscript online: 25 APR 2011 07:36AM EST
  4. Manuscript Accepted: 13 APR 2011
  5. Manuscript Received: 16 MAR 2011

Funded by

  • Dutch Diabetes Research Foundation. Grant Number: 2004.00.059
  • Netherlands Organization for Health Research and Development. Grant Number: 9120.6050
  • Netherlands Organization for Scientific Research. Grant Numbers: 917.66.359, 918.96.618

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    S. Paglialunga, B. Bree, M. Bosma, M. P. Valdecantos, E. Amengual-Cladera, J. A. Jörgensen, D. Beurden, G. J. M. Hartog, D. M. Ouwens, J. J. Briedé, P. Schrauwen, J. Hoeks, Targeting of mitochondrial reactive oxygen species production does not avert lipid-induced insulin resistance in muscle tissue from mice, Diabetologia, 2012, 55, 10, 2759

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