Conflict of interest: None.
Induced Neural Lineage Cells as Repair Kits: So Close, Yet So Far Away
Article first published online: 21 FEB 2014
© 2013 Wiley Periodicals, Inc.
Journal of Cellular Physiology
Volume 229, Issue 6, pages 728–742, June 2014
How to Cite
Mirakhori, F., Zeynali, B., Salekdeh, G. H. and Baharvand, H. (2014), Induced Neural Lineage Cells as Repair Kits: So Close, Yet So Far Away. J. Cell. Physiol., 229: 728–742. doi: 10.1002/jcp.24509
- Issue published online: 21 FEB 2014
- Article first published online: 21 FEB 2014
- Accepted manuscript online: 15 NOV 2013 06:26AM EST
- Manuscript Accepted: 6 NOV 2013
- Manuscript Received: 24 SEP 2013
- Royan Institute
Transdifferentiation or direct reprogramming of somatic cells into neural lineage cells has provided an invaluable new tool to advance the regenerative neural medicine. Here, we provide an overview of the various strategies currently available for producing of induced neural lineage cells in vitro as well as the direct reprogramming of neural cells in vivo. We also discussing some of the challenges faced in harnessing the potential of induced neural lineage cells for biomedical applications. J. Cell. Physiol. 229: 728–742, 2014. © 2013 Wiley Periodicals, Inc.