Trial Registration No.: ACTRN12613000146796 (Australian New Zealand Clinical Trials Registry, ANZCTR).
Effectiveness of a Pharmacist-Led Drug Counseling on Enhancing Antihypertensive Adherence and Blood Pressure Control: A Randomized Controlled Trial
Article first published online: 16 MAY 2013
© The Author(s) 2013
The Journal of Clinical Pharmacology
Volume 53, Issue 7, pages 753–761, July 2013
How to Cite
Wong, M. C.S., Liu, K. Q.L., Wang, H. H.X., Lee, C. L.S., Kwan, M. W.M., Lee, K. W.S., Cheung, Y., Lee, G. K.Y., Morisky, D. E. and Griffiths, S. M. (2013), Effectiveness of a Pharmacist-Led Drug Counseling on Enhancing Antihypertensive Adherence and Blood Pressure Control: A Randomized Controlled Trial. Journal of Clinical Pharma, 53: 753–761. doi: 10.1002/jcph.101
- Issue published online: 21 JUN 2013
- Article first published online: 16 MAY 2013
- Manuscript Accepted: 16 APR 2013
- Manuscript Received: 17 MAR 2013
- clinical practice;
- medication counseling;
- pharmacist intervention
Adherence to antihypertensive medications represents a crucial success factor for optimal blood pressure (BP) control in clinical practice. This study evaluated whether an additional pharmacist-led medication counseling could achieve better optimal BP control and enhance compliance. In a designated family clinic in a region with similar resident characteristics to Hong Kong, patients taking ≥ one antihypertensive agent with suboptimal compliance were randomly allocated to a brief 3-minute drug advice (control; n = 161) or pharmacist counseling (intervention; n = 113). The two groups were compared by repeated measure ANOVA at 3-months and 6-months with BP control and medication compliance as outcome variables, respectively. The proportions of patients having optimal compliance increased from 0% to 41.1% at 3 months and 61.9% at 6 months (P < 0.001). The proportion of patients having optimal BP control improved from 64.1% at baseline to 74.0% at 3 months and 74.5% at 6 months (P = 0.023). There were no significant differences between the two groups in the changes of BP control and compliance levels. This study implied that even a brief 3-minute drug advice might lead to improved BP levels among patients on antihypertensive medications in general practice, but did not demonstrate additional effects by pharmacist counseling.