The Journal of Clinical Pharmacology

Cover image for The Journal of Clinical Pharmacology

January 2006

Volume 46, Issue 1

Pages 6–114

  1. Forum

    1. Top of page
    2. Forum
    3. Therapeutic Review
    4. Clinical Studies
    5. Pharmacokinetics
    6. Pharmacokinetics and Pharmacodynamics
    7. Drug Metabolism
    8. Drug Interactions
    1. Challenges and Opportunities for Pharmacoepidemiology in Drug-Therapy Decision Making (pages 6–9)

      Dr Mahyar Etminan, Dr Sudeep Gill, Mr Mark FitzGerald and Dr Ali Samii

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283285

  2. Therapeutic Review

    1. Top of page
    2. Forum
    3. Therapeutic Review
    4. Clinical Studies
    5. Pharmacokinetics
    6. Pharmacokinetics and Pharmacodynamics
    7. Drug Metabolism
    8. Drug Interactions
    1. An Overview of the Pharmacokinetics and Pharmacodynamics of Efalizumab: A Monoclonal Antibody Approved for Use in Psoriasis (pages 10–20)

      Dr Amita Joshi, Dr Robert Bauer, Dr Peter Kuebler, Mr Mark White, Ms Cecelia Leddy, Mr Peter Compton, Dr Marvin Garovoy, Dr Paul Kwon, Dr Patricia Walicke and Dr Russell Dedrick

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283282

  3. Clinical Studies

    1. Top of page
    2. Forum
    3. Therapeutic Review
    4. Clinical Studies
    5. Pharmacokinetics
    6. Pharmacokinetics and Pharmacodynamics
    7. Drug Metabolism
    8. Drug Interactions
    1. The Impact of Suppressing the Renin-Angiotensin System on Atrial Fibrillation (pages 21–28)

      Dr James S. Kalus, Dr Craig I. Coleman and Dr C. Michael White

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283284

  4. Pharmacokinetics

    1. Top of page
    2. Forum
    3. Therapeutic Review
    4. Clinical Studies
    5. Pharmacokinetics
    6. Pharmacokinetics and Pharmacodynamics
    7. Drug Metabolism
    8. Drug Interactions
    1. A Single-Dose Pharmacokinetic Study of Lasofoxifene in Healthy Volunteers and Subjects With Mild and Moderate Hepatic Impairment (pages 29–36)

      Candace Bramson, Daniele Ouellet, Doina Roman, Edward Randinitis and Mark J. Gardner

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283278

    2. Pharmacokinetics of Otamixaban, a Direct Factor Xa Inhibitor, in Healthy Male Subjects: Pharmacokinetic Model Development for Phase 2/3 Simulation of Exposure (pages 37–44)

      Dr Anne Paccaly, Dr Annke Frick, Dr Shashank Rohatagi, Dr Jingli Liu, Dr Umesh Shukla, Dr Ronald Rosenburg, Dr Markus Hinder and Dr Bradford K. Jensen

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005281817

  5. Pharmacokinetics and Pharmacodynamics

    1. Top of page
    2. Forum
    3. Therapeutic Review
    4. Clinical Studies
    5. Pharmacokinetics
    6. Pharmacokinetics and Pharmacodynamics
    7. Drug Metabolism
    8. Drug Interactions
    1. Pharmacokinetic/Pharmacodynamic Relationships for Otamixaban, a Direct Factor Xa Inhibitor, in Healthy Subjects (pages 45–51)

      Dr Anne Paccaly, Dr Annke Frick, Dr Marie-Laure Ozoux, Dr Valeria Chu, Dr Ronald Rosenburg, Dr Markus Hinder, Dr Umesh Shukla and Dr Bradford K. Jensen

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005281818

    2. Clinical Pharmacology of Multiple Doses of Lasofoxifene in Postmenopausal Women (pages 52–58)

      Mark Gardner, Ann Taylor, Greg Wei, Albert Calcagni Jr, Barbara Duncan and Ashley Milton

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283280

    3. Population Pharmacokinetic and Pharmacodynamic Analysis of a Class IC Antiarrhythmic, Pilsicainide, in Patients With Cardiac Arrhythmias (pages 59–68)

      Mr Ryuichi Ogawa, Dr Ryoji Kishi, Dr Kiyoshi Mihara, Dr Harumi Takahashi, Dr Akihiko Takagi, Dr Naoki Matsumoto, Dr Keisou Masuhara, Dr Kiyoshi Nakazawa, Dr Fumihiko Miyake, Dr Shinichi Kobayashi and Dr Hirotoshi Echizen

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283281

    4. Population Pharmacokinetics and Pharmacodynamics of Meropenem in Pediatric Patients (pages 69–75)

      Xiaoli Du, Chonghua Li, Joseph L. Kuti, Charles H. Nightingale and David P. Nicolau

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283283

    5. A Comparative Study of Sirolimus Tablet Versus Oral Solution for Prophylaxis of Acute Renal Allograft Rejection (pages 76–87)

      Mr Timothy H. Mathew, Dr Charles Van Buren, Dr Barry D. Kahan, Dr Khalid Butt, Dr Sundaram Hariharan, Dr James J. Zimmerman and Rapamune 309 Study Group

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005282628

  6. Drug Metabolism

    1. Top of page
    2. Forum
    3. Therapeutic Review
    4. Clinical Studies
    5. Pharmacokinetics
    6. Pharmacokinetics and Pharmacodynamics
    7. Drug Metabolism
    8. Drug Interactions
    1. The Effect of Oral Pleconaril on Hepatic Cytochrome P450 3A Activity in Healthy Adults Using Intravenous Midazolam as a Probe (pages 103–108)

      Dr Joseph D. Ma, Dr Anne N. Nafziger, Dr Gerry Rhodes, Dr Siyu Liu, Ms Anne M. Gartung and Dr Joseph S. Bertino Jr

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005283286

  7. Drug Interactions

    1. Top of page
    2. Forum
    3. Therapeutic Review
    4. Clinical Studies
    5. Pharmacokinetics
    6. Pharmacokinetics and Pharmacodynamics
    7. Drug Metabolism
    8. Drug Interactions
    1. Effect of High-Dose Aspirin on CYP2E1 Activity in Healthy Subjects Measured Using Chlorzoxazone as a Probe (pages 109–114)

      Dr Ji-Young Park, Dr Kyoung-Ah Kim, Dr Pil-Whan Park and Dr Jong-Myung Ha

      Article first published online: 7 MAR 2013 | DOI: 10.1177/0091270005282635

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