The Journal of Clinical Pharmacology

Cover image for The Journal of Clinical Pharmacology

February 2013

Volume 53, Issue 2

Pages 119–239

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. Review
    4. Original Articles
    5. Brief Reports
    1. You have free access to this content
      Issue Information (pages 119–239)

      Version of Record online: 22 FEB 2013 | DOI: 10.1002/jcph.71

  2. Review

    1. Top of page
    2. Issue Information
    3. Review
    4. Original Articles
    5. Brief Reports
    1. Pharmacokinetic Properties ofAnti-Influenza Neuraminidase Inhibitors (pages 119–139)

      Kalayanee Chairat, Joel Tarning, Nicholas J. White and Niklas Lindegardh

      Version of Record online: 24 JAN 2013 | DOI: 10.1177/0091270012440280

  3. Original Articles

    1. Top of page
    2. Issue Information
    3. Review
    4. Original Articles
    5. Brief Reports
    1. Pharmacokinetics and Pharmacodynamics

      The Pharmacokinetics and Pharmacodynamics of Zaleplon Delivered as a Thermally Generated Aerosol in a Single Breath to Volunteers (pages 140–150)

      Michael J. Avram, Daniel A. Spyker, John H. Kehne and James V. Cassella

      Version of Record online: 22 FEB 2013 | DOI: 10.1177/0091270012436886

    2. You have free access to this content
    3. The Combination of Exposure-Response and Case-Control Analyses in Regulatory Decision Making (pages 160–166)

      Jun Yang, Hong Zhao, Christine Garnett, Atiqur Rahman, Jogarao V. Gobburu, William Pierce, Genevieve Schechter, Jeffery Summers, Patricia Keegan, Brian Booth and Yaning Wang

      Version of Record online: 24 JAN 2013 | DOI: 10.1177/0091270012445206

    4. Pharmacokinetics

      Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 1: Volume of Distribution at Steady State (pages 167–177)

      Franco Lombardo, Nigel J. Waters, Upendra A. Argikar, Michelle K. Dennehy, Jenny Zhan, Mithat Gunduz, Shawn P. Harriman, Giuliano Berellini, Ivana Liric Rajlic and R. Scott Obach

      Version of Record online: 24 JAN 2013 | DOI: 10.1177/0091270012440281

      Corrected by:

      Errata: Erratum

      Vol. 53, Issue 5, 574, Version of Record online: 17 APR 2013

    5. Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 2: Clearance (pages 178–191)

      Franco Lombardo, Nigel J. Waters, Upendra A. Argikar, Michelle K. Dennehy, Jenny Zhan, Mithat Gunduz, Shawn P. Harriman, Giuliano Berellini, Ivana Liric Rajlic and R. Scott Obach

      Version of Record online: 24 JAN 2013 | DOI: 10.1177/0091270012440282

    6. Comparison of Subcutaneous and Intravenous Administration of Trastuzumab: A Phase I/Ib Trial in Healthy Male Volunteers and Patients With HER2-Positive Breast Cancer (pages 192–201)

      Chris Wynne, Vernon Harvey, Christian Schwabe, Devonie Waaka, Christine McIntyre and Beate Bittner

      Version of Record online: 22 FEB 2013 | DOI: 10.1177/0091270012436560

    7. Steady-State Pharmacokinetics of Etravirine and Lopinavir/Ritonavir Melt Extrusion Formulation, Alone and in Combination, in Healthy HIV-Negative Volunteers (pages 202–210)

      Monika Schöller-Gyüre, Thomas N. Kakuda, James Witek, Sophie H. Akuma, Goedele De Smedt, Kurt Spittaels, Veerle Vyncke and Richard M.W. Hoetelmans

      Version of Record online: 24 JAN 2013 | DOI: 10.1177/0091270012445205

    8. Pharmacodynamics

      Clinical Risk Factors for Adverse Events in Allopurinol Users (pages 211–216)

      Hee Jung Ryu, Ran Song, Hye Won Kim, Jin Hyun Kim, Eun Young Lee, Yun Jong Lee, Yeong Wook Song and Eun Bong Lee

      Version of Record online: 22 FEB 2013 | DOI: 10.1177/0091270012439715

    9. Drug Interactions

      Inhibitory Effect of Ketoconazole on the Pharmacokinetics of a Multireceptor Tyrosine Kinase Inhibitor BMS-690514 in Healthy Participants: Assessing the Mechanism of the Interaction With Physiologically-Based Pharmacokinetic Simulations (pages 217–227)

      Zheng Yang, Blisse Vakkalagadda, Guoxiang Shen, Christoph M. Ahlers, Teresa Has, Lisa J. Christopher, John F. Kurland, Vikram Roongta, Eric Masson and Steven Zhang

      Version of Record online: 22 FEB 2013 | DOI: 10.1177/0091270012439208

  4. Brief Reports

    1. Top of page
    2. Issue Information
    3. Review
    4. Original Articles
    5. Brief Reports
    1. Population Pharmacokinetic Modeling of Sertraline Treatment in Patients With Alzheimer Disease: The DIADS-2 Study (pages 234–239)

      Claire H. Li, Bruce G. Pollock, Constantine G. Lyketsos, Vijay Vaidya, Lea T. Drye, Margaret Kirshner, Denise Sorisio and Robert R. Bies

      Version of Record online: 24 JAN 2013 | DOI: 10.1177/0091270012445793

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