Ultrastructural study of the intracellular behavior of four mineral elements in the lactating mammary gland cells: Study using conventional transmission electron microscopy
Version of Record online: 10 SEP 2008
Copyright © 2008 Wiley-Liss, Inc.
Microscopy Research and Technique
Volume 71, Issue 12, pages 849–855, December 2008
How to Cite
Ahlem, A., Samira, M., Ali, E. H., Pierre, G. and Leila, T. (2008), Ultrastructural study of the intracellular behavior of four mineral elements in the lactating mammary gland cells: Study using conventional transmission electron microscopy. Microsc. Res. Tech., 71: 849–855. doi: 10.1002/jemt.20628
- Issue online: 18 NOV 2008
- Version of Record online: 10 SEP 2008
- Manuscript Accepted: 18 JUL 2008
- Manuscript Received: 15 MAY 2008
- mammary gland;
- IIIA group elements;
The effects of parenteral injection of aluminum, indium, gadolinium, or terbium in rats have been previously studied in several organs such as the liver, the kidneys, etc., but never in mammary glands. In this work, we have attempted to study the subcellular localization of these elements after their intraperitoneal administration. Their subsequent effects in the lactating mammary gland cells have also been studied. Our results using conventional transmission electron microscopy have shown that the lysosomes of the mammary glandular epithelial cells are the intracellular site of accumulation of the studied elements. Our results have also show intracellular deteriorations such as an expanded ergastoplasm and altered mitochondria after intraperitoneal injection of aluminum and indium. Microsc. Res. Tech., 2008. © 2008 Wiley-Liss, Inc.