Research Article

A soft-cache strategy for pathologist's navigation in virtual microscopy

  1. Francisco Gómez,
  2. Diana Marín,
  3. Eduardo Romero*

Article first published online: 9 SEP 2010

DOI: 10.1002/jemt.20923

Issue

Microscopy Research and Technique

Microscopy Research and Technique

Volume 74, Issue 5, pages 401–414, May 2011

Additional Information

How to Cite

Gómez, F., Marín, D. and Romero, E. (2011), A soft-cache strategy for pathologist's navigation in virtual microscopy. Microsc. Res. Tech., 74: 401–414. doi: 10.1002/jemt.20923

Author Information

  1. Bioingenium Research Group, Cra 30 No 45 03-Ciudad Universitaria, Faculty of Medicine, National University of Colombia, Bogotá DC, Colombia

*Telemedicine Centre, Bioingenium Research Group, Cra 30 No 45 03-Ciudad Universitaria, Faculty of Medicine, Building 471, National University of Colombia, Bogotá DC, Colombia

Publication History

  1. Issue published online: 14 APR 2011
  2. Article first published online: 9 SEP 2010
  3. Manuscript Accepted: 15 JUL 2010
  4. Manuscript Received: 25 MAR 2010

Funded by

  • Pathology Department of the National University
  • Colombian Research Agency, Colciencias. Grant Number: Project number 1101-487-26000

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Keywords:

  • virtual microscopy;
  • pathologists navigation;
  • soft-cache;
  • browsing

Abstract

Navigation through large microscopical images demands special characteristics like flexibility to access image data and progressive recovery or relevant information, i.e., several qualities, magnifications, and random accesses to any desired Window of Interest in the Virtual Slide (VS). Nowadays there exist systems that allow such interaction, but with a certain delay, which is dependent on the application. It has been shown that caching or prefetching policies can speed up interaction with these systems. This article presents an optimal soft-cache strategy, which improves the navigation times in virtual microscopy. The entire method includes an optimal soft-cache strategy and a dynamical probabilistic model of a pathologist's navigation. This strategy was implemented as a Client-Server application, using the JPEG2000-JPIP standard and evaluated using different navigation patterns, namely, four different pathologists exploring 10 VS, stained with different dyes. The present approach was compared with a conventional soft-cache method and the cache performance improved, in average, in about a 10%. Microsc. Res. Tech., 2011. © 2010 Wiley-Liss, Inc.

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