Qualitative study of young, adult, and aged wistar rats temporomandibular synovial membrane employing light, scanning, and transmission electron microscopy
Article first published online: 12 JUL 2012
Copyright © 2012 Wiley Periodicals, Inc.
Microscopy Research and Technique
Volume 75, Issue 11, pages 1522–1527, November 2012
How to Cite
Duro, C. C., Ciena, A. P., De Almeida, S. R. Y., Da Silva Righetti, M. M., De Freitas Grisolia, D., Issa, J. P. M., Da Silva, M. C. P. and Watanabe, I.-s. (2012), Qualitative study of young, adult, and aged wistar rats temporomandibular synovial membrane employing light, scanning, and transmission electron microscopy. Microsc. Res. Tech., 75: 1522–1527. doi: 10.1002/jemt.22095
- Issue published online: 22 OCT 2012
- Article first published online: 12 JUL 2012
- Manuscript Accepted: 11 JUN 2012
- Manuscript Received: 8 DEC 2011
- temporomandibular joint;
- synovial membrane;
- microscopy, electron
The aim of this study was to analyze the rat temporomandibular joint (TMJ) synovial membrane at different ages using light, scanning, and transmission electron microscopy. Under light microscopic analysis, the TMJ structures were observed such as condyle, capsule, disk, the synovial membrane collagen type, and cells distribution. In the scanning electron microscopy, the synovial membrane surface exhibited a smooth aspect in young animals and there was an increase with ageing in the number of folds. The transmission electron microscopic analysis showed more synoviocytes in the synovial layer in the young group and still a great number of vesicles and cisterns dilation of rough endoplasmic reticulum in the aged group. In the three groups, a dense layer of collagen fibers in the synovial layer and cytoplasmic extensions were clearly seen. It was possible to conclude that synovial membrane structures in aged group showed alterations contributing to the decrease in joint lubrication and in the sliding between disk and joint surfaces. These characteristic will reflect in biomechanics of chewing, and may cause the TMJ disorders, currently observed in clinical processes. Microsc. Res. Tech. © 2012 Wiley Periodicals, Inc.