Comparative Physiology and Biochemistry
The effects of epilation and hormones on the activity of rat hair follicles
Article first published online: 13 MAY 2005
Copyright © 1975 Wiley-Liss, Inc., A Wiley Company
Journal of Experimental Zoology
Volume 191, Issue 1, pages 49–62, January 1975
How to Cite
Hale, P. A. and Ebling, F. J. (1975), The effects of epilation and hormones on the activity of rat hair follicles. J. Exp. Zool., 191: 49–62. doi: 10.1002/jez.1401910106
- Issue published online: 13 MAY 2005
- Article first published online: 13 MAY 2005
The growth of hair from epilated and non-epilated areas of rats receiving a variety of hormonal treatments was investigated by pulse-labelling with 35S-cystine. While epilation at certain stages of the spontaneous cycle may rephase follicular activity, it did not affect the length, rate or duration of growth of the hairs which erupted subsequently, either in untreated or hormone-treated rats.
Thyroxine shortened the active as well as the resting phase of the follicular cycle. It also increased the growth rate, so that hairs were ultimately the same length as those from untreated animals. Estradiol slightly shortened the duration of the active phase, even though the complete cycle was prolonged. It also decreased the hair growth rate. When administered simultaneously, estradiol and thyroxine exerted their effects independently.