The Role of Brain Peptides in the Reproduction of Blue Gourami Males (Trichogaster trichopterus)
Article first published online: 15 JUL 2013
© 2013 Wiley Periodicals, Inc.
Journal of Experimental Zoology Part A: Ecological Genetics and Physiology
Volume 319, Issue 8, pages 461–470, October 2013
How to Cite
2013. The role of brain peptides in the reproduction of blue gourami males (Trichogaster trichopterus). J. Exp. Zool. 319A:461–470., .
- Issue published online: 11 SEP 2013
- Article first published online: 15 JUL 2013
- Manuscript Accepted: 9 JUN 2013
- Manuscript Revised: 22 MAY 2013
- Manuscript Received: 29 APR 2013
In all vertebrates, reproduction and growth are closely linked and both are controlled by complex hormonal interactions at the brain-pituitary level. In this study, we focused on the reciprocal interactions between brain peptides that regulate growth and reproductive functions in a teleostei fish (blue gourami Trichogaster trichopterus). An increase in gonadotropin-releasing hormone 1 (GnRH1) gene expression was detected during ontogeny, and this peptide increased growth hormone (GH) and β follicle-stimulating hormone (βFSH) gene expression in pituitary cell culture. However, although no change in gonadotropin-releasing hormone 2 (GnRH2) gene expression during the reproductive cycle or sexual behavior was detected, a stimulatory effect of this peptide on β gonadotropins (βGtH) gene expression was observed. In addition, pituitary adenylate cyclase-activating polypeptide 38 (PACAP-38) inhibited GnRH-analog-induced βFSH gene expression, and co-treatment of cells with GnRH-analog and PACAP-38 inhibited GnRH-analog-stimulatory and PACAP-38-inhibitory effects on GH gene expression. These findings together with previous studies were used to create a model summarizing the mechanism of brain peptides (GnRH, PACAP and its related peptide) and the relationship to reproduction and growth through pituitary hormone gene expression during ontogenesis and reproductive stages in blue gourami. J. Exp. Zool. 319A: 461–470, 2013. © 2013 Wiley Periodicals, Inc.