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Abstract

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The chalcones 1-(2′-hydroxy-aryl)-3-(1-indol-3-yl)-prop-2-en-1-one (3) and 1-(2′-hydroxy-aryl)-3-(2-chloroquinolin-3-yl)-prop-2-en-1-one (6) were synthesised by piperidine mediated condensation of an ethanolic solution of an o-hydroxyacetophenone (1) with corresponding heteroaryl-3-carboxaldehyde. The structures have been established on the basis of elemental (C, H, N) analysis, UV, IR, 1H NMR spectral data. The compounds 3 and 6 were screened for antimicrobial activities against a variety of bacterial agents. J. Heterocyclic Chem., 2010.

Featured Compounds

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  1. 1 - 21
Compound 3
Molecular Weight:Not Available
Molecular Formula:Not Available
InChIKey:Not Available
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Compound 6
Molecular Weight:Not Available
Molecular Formula:Not Available
InChIKey:Not Available
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Compound 2
Molecular Weight:145.158
Molecular Formula:C9H7NO
InChIKey:OLNJUISKUQQNIM-UHFFFAOYSA-N
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Compound 5
Molecular Weight:191.614
Molecular Formula:C10H6ClNO
InChIKey:SDKQWXCBSNMYBN-UHFFFAOYSA-N
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Compound 1
Molecular Weight:Not Available
Molecular Formula:Not Available
InChIKey:Not Available
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Compound 1a
Molecular Weight:166.1739
Molecular Formula:C9H10O3
InChIKey:UILPJVPSNHJFIK-UHFFFAOYSA-N
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Compound 1b
Molecular Weight:166.1739
Molecular Formula:C9H10O3
InChIKey:MLIBGOFSXXWRIY-UHFFFAOYSA-N
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Compound 1c
Molecular Weight:196.1999
Molecular Formula:C10H12O4
InChIKey:BCEPNLMYVYJIHU-UHFFFAOYSA-N
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Compound 1d
Molecular Weight:226.2259
Molecular Formula:C11H14O5
InChIKey:WLTFZNFPHXCIAO-UHFFFAOYSA-N
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Compound 1e
Molecular Weight:196.1999
Molecular Formula:C10H12O4
InChIKey:FBUBVLUPUDBFME-UHFFFAOYSA-N
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Compound 3a
Molecular Weight:293.3166
Molecular Formula:C18H15NO3
InChIKey:FBEVRNKVAMTEHP-RMKNXTFCSA-N
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Compound 3b
Molecular Weight:293.3166
Molecular Formula:C18H15NO3
InChIKey:JCZLGRSZTAYIRZ-SOFGYWHQSA-N
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Compound 3c
Molecular Weight:323.3426
Molecular Formula:C19H17NO4
InChIKey:SHDLXPHBCSHYAJ-VQHVLOKHSA-N
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Compound 3d
Molecular Weight:353.3686
Molecular Formula:C20H19NO5
InChIKey:LEVMUMFQVIPYLL-CMDGGOBGSA-N
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Compound 3e
Molecular Weight:323.3426
Molecular Formula:C19H17NO4
InChIKey:CAZYCGZAMQVYRB-BQYQJAHWSA-N
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Compound 4
Molecular Weight:135.1632
Molecular Formula:C8H9NO
InChIKey:FZERHIULMFGESH-UHFFFAOYSA-N
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Compound 6a
Molecular Weight:339.772
Molecular Formula:C19H14ClNO3
InChIKey:JLRFOQKQWVMNAB-RMKNXTFCSA-N
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Compound 6b
Molecular Weight:339.772
Molecular Formula:C19H14ClNO3
InChIKey:UGVCAULPKHWPJI-SOFGYWHQSA-N
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Compound 6c
Molecular Weight:369.798
Molecular Formula:C20H16ClNO4
InChIKey:JWQWZBMXPKJWDL-VQHVLOKHSA-N
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Compound 6d
Molecular Weight:399.824
Molecular Formula:C21H18ClNO5
InChIKey:BLVBDGMQUHWSBT-CMDGGOBGSA-N
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Compound 6e
Molecular Weight:369.798
Molecular Formula:C20H16ClNO4
InChIKey:IQALDBQYHIGANX-BQYQJAHWSA-N
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