Cyclization of 5-amino-1-β-d-ribofuranosylimidazole-4-carboxamide (AICA-riboside): A review
Article first published online: 3 APR 2009
Copyright © 1978 Journal of Heterocyclic Chemistry
Journal of Heterocyclic Chemistry
Volume 15, Issue 3, pages 353–358, May 1978
How to Cite
Yamazaki, A. and Okutsu, M. (1978), Cyclization of 5-amino-1-β-d-ribofuranosylimidazole-4-carboxamide (AICA-riboside): A review. J. Heterocyclic Chem., 15: 353–358. doi: 10.1002/jhet.5570150301
- Issue published online: 3 APR 2009
- Article first published online: 3 APR 2009
- Manuscript Received: 28 SEP 1977
- Ajinomoto Co., Inc.
The synthesis of various purine nucleosides by cyclization of AICA-riboside(5-amino-1-β-D-ribofuranosylimidazole-4-carboxamide) is described. A variety of cyclization reactions provide new synthetic routes to inosine and guanosine. In this review, emphasis will be placed on the synthesis of the latter.