Article

Formation of aryl-bis (6-amino-1,3-dimethyluracil-5-yl) methanes by reaction of 6-amino-1, 3-dimethyluracil with aromatic aldehydes

  1. Ranju Bansal1,
  2. R. Sunil Kumar1,
  3. Gulshan Kumar1,
  4. Sridhar Thota1,
  5. S. Thamotharan2,
  6. V. Parthasarathi3,
  7. Anthony Linden4

Article first published online: 13 MAR 2009

DOI: 10.1002/jhet.5570450636

Issue

Journal of Heterocyclic Chemistry

Journal of Heterocyclic Chemistry

Volume 45, Issue 6, pages 1789–1795, November/December 2008

Additional Information

How to Cite

Bansal, R., Kumar, R. S., Kumar, G., Thota, S., Thamotharan, S., Parthasarathi, V. and Linden, A. (2008), Formation of aryl-bis (6-amino-1,3-dimethyluracil-5-yl) methanes by reaction of 6-amino-1, 3-dimethyluracil with aromatic aldehydes. J. Heterocyclic Chem., 45: 1789–1795. doi: 10.1002/jhet.5570450636

Author Information

  1. 1

    University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh-160014, India

  2. 2

    Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012, India

  3. 3

    School of Physics, Bharathidasan University, Tiruchirappalli-620024, India

  4. 4

    Institute of Organic Chemistry, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

Publication History

  1. Issue published online: 13 MAR 2009
  2. Article first published online: 13 MAR 2009
  3. Manuscript Received: 26 NOV 2007

Funded by

  • University Grants Commission

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Abstract

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The synthesis of aryl-bis(6-amino-1,3-dimethyluracil-5-yl)-methanes 3a-m by condensation of 6-amino-1,3-dimethyluracil (1) with aromatic aldehydes 2a-m at room temperature is reported. The structures of the compounds were established using various spectroscopic analyses and X-ray crystallography. The crystal structures of two aryl-bis (6-amino-1,3-dimethyluracil-5-yl) methanes are presented.

Featured Compounds

Compound Information
Molecular Weight:398.4158
Molecular Formula:C19H22N6O4
InChIKey:PYHIELQPCATJBF-UHFFFAOYSA-N
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Compound Information
Molecular Weight:458.4677
Molecular Formula:C21H26N6O6
InChIKey:KDGXTKSONZUWEN-UHFFFAOYSA-N
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Compound Information
Molecular Weight:488.4937
Molecular Formula:C22H28N6O7
InChIKey:KNBHIQNMWVJSKA-UHFFFAOYSA-N
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Compound Information
Molecular Weight:428.4418
Molecular Formula:C20H24N6O5
InChIKey:LVZPHCJNNJVBIE-UHFFFAOYSA-N
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Compound Information
Molecular Weight:442.4253
Molecular Formula:C20H22N6O6
InChIKey:HJCLOSXWZVHQAH-UHFFFAOYSA-N
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Compound Information
Molecular Weight:440.4955
Molecular Formula:C22H28N6O4
InChIKey:FUZHXBQSUZDCPO-UHFFFAOYSA-N
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Compound Information
Molecular Weight:399.4038
Molecular Formula:C18H21N7O4
InChIKey:OGNTYTRITPQOGN-UHFFFAOYSA-N
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Compound Information
Molecular Weight:399.4038
Molecular Formula:C18H21N7O4
InChIKey:ADSAJZNIAMDQLI-UHFFFAOYSA-N
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Compound Information
Molecular Weight:444.4412
Molecular Formula:C20H24N6O6
InChIKey:MESWNLZLKFBZIS-UHFFFAOYSA-N
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Compound Information
Molecular Weight:414.4152
Molecular Formula:C19H22N6O5
InChIKey:VJVNERROWOZTTR-UHFFFAOYSA-N
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Compound Information
Molecular Weight:541.5994
Molecular Formula:C26H35N7O6
InChIKey:FDGBDZMCHZDQRP-UHFFFAOYSA-N
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Compound Information
Molecular Weight:520.966
Molecular Formula:C23H29ClN6O6
InChIKey:KDHYTXDFABBVQW-UHFFFAOYSA-N
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Compound Information
Molecular Weight:552.5823
Molecular Formula:C26H32N8O6
InChIKey:UMLYJPJSQMZAOC-UHFFFAOYSA-N
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