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Keywords:

  • Oxygen-18 and deuterium labelled compounds;
  • 3-phenyl-2-propenoic and 3-phenyl-2-propynoic acids

Abstract

3-Phenyl-2-propenoic (cinnamic) and 3- [2H5] -phenyl-2- propenoic 80O-bilabelled acids (2c,d) are prepared via alkaline hydrolysis of styrylisoxazoles (1a,b). The same reaction carried out on the vic-dibromocompounds (3a,b) gave the 3-phenyl-2-propynoic (phenylpropiolic) and 3-[2H5]-Phenyl-2-propynoic 18O-bilabelled acids (4c,d), respectively.