Supported by NIH training grant 5-T01-GM 00312 (PWT), the Muscular Dystrophy Association (BMC) and a Rackham Grant and NIH-HD 08150 (TGC).
A staging system for forelimb regeneration in the axolotl, Ambystoma mexicanum†
Article first published online: 6 FEB 2005
Copyright © 1976 Wiley-Liss, Inc.
Journal of Morphology
Volume 150, Issue 1, pages 117–128, September 1976
How to Cite
Tank, P. W., Carlson, B. M. and Connelly, T. G. (1976), A staging system for forelimb regeneration in the axolotl, Ambystoma mexicanum. J. Morphol., 150: 117–128. doi: 10.1002/jmor.1051500106
- Issue published online: 6 FEB 2005
- Article first published online: 6 FEB 2005
A staging system has been devised for normal regeneration from the upper arm in the mature axolotl. It consists of seven externally definable stages: (1) Wound healing (WH); (2) Dedifferentiation (DD); (3) Early bud (EB); (4) Medium bud (MB); (5) Late bud (LB); (6) Palette (Pal), and (7) Digital outgrowth (DO). Serial histological sections of 38 regenerating limbs were used to correlate gross stages with microscopic events in the regenerative process.