The structure of the caudal wall of the zebrafish (Danio rerio) swim bladder: Evidence of localized lamellar body secretion and a proximate neural plexus
Article first published online: 19 MAR 2014
© 2014 Wiley Periodicals, Inc.
Journal of Morphology
Volume 275, Issue 8, pages 933–948, August 2014
How to Cite
Robertson, G. N., Croll, R. P. and Smith, F. M. (2014), The structure of the caudal wall of the zebrafish (Danio rerio) swim bladder: Evidence of localized lamellar body secretion and a proximate neural plexus. J. Morphol., 275: 933–948. doi: 10.1002/jmor.20274
- Issue published online: 4 JUL 2014
- Article first published online: 19 MAR 2014
- Manuscript Accepted: 25 FEB 2014
- Manuscript Revised: 11 FEB 2014
- Manuscript Received: 16 DEC 2013
- Canadian Space Agency. Grant Number: #046016/001/ST
- Natural Sciences and Engineering Council of Canada. Grant Number: #38863-02 (Discovery Grant)
- autonomic nervous system;
In this study, we present a morphological description of the fine structure of the tissues composing the caudal tip of the adult zebrafish swim bladder and an immunochemical survey of the innervation at this site. The internal aspect of the caudal tip is lined by an epithelium specialized to secrete surfactant into the lumen as evinced by the exocytosis of lamellar bodies. The sole innervation to this region consists of a neural plexus, present on the external surface, of nitric oxide synthase-positive (nNOS) neuronal cell bodies that are contacted by axon terminals, some containing neuropeptide Y and vasoactive intestinal polypeptide. As the specialized epithelium and neural plexus are coincident and of common extent, we suggest that the morphological relationship between the two elements allows the nervous system to affect surfactant processing, possibly through a paracrine mechanism. J. Morphol. 275:933–948, 2014. © 2014 Wiley Periodicals, Inc.