This article originally appeared in the 21st volume of Chemical Sensors (Chinese) and is reprinted here with permission.
BIACORE J: a new platform for routine biomolecular interaction analysis†
Article first published online: 11 JUL 2001
Copyright © 2001 John Wiley & Sons, Ltd.
Journal of Molecular Recognition
Volume 14, Issue 4, pages 223–228, July/August 2001
How to Cite
Rich, R. L. and Myszka, D. G. (2001), BIACORE J: a new platform for routine biomolecular interaction analysis. J. Mol. Recognit., 14: 223–228. doi: 10.1002/jmr.535
- Issue published online: 11 JUL 2001
- Article first published online: 11 JUL 2001
- Manuscript Accepted: 5 APR 2001
- Manuscript Received: 23 MAR 2001
- surface plasmon resonance
SPR biosensor technology continues to evolve. The recently released platform from Biacore AB (Uppsala, Sweden), BIACORE J, is designed for the routine analysis of biomolecular interactions. Using an antibody–protein A and a ligand–receptor system, we demonstrate the utility of BIACORE J in determining active concentration and binding affinities. The results from these studies illustrate the high sensitivity of the instrument and its ability to generate reproducible binding responses. The BIACORE J is easy to operate and useful in diverse applications, making SPR technology widely accessible as a research tool. Copyright © 2001 John Wiley & Sons, Ltd.