Review Article

Elusive recognition determinants for ubiquitination

  1. Amit Banerjee1,*,
  2. Rebecca C. Wade2,3,*

Article first published online: 18 FEB 2002

DOI: 10.1002/jmr.561

Issue

Journal of Molecular Recognition

Journal of Molecular Recognition

Volume 15, Issue 1, pages 3–5, January/February 2002

Additional Information

How to Cite

Banerjee, A. and Wade, R. C. (2002), Elusive recognition determinants for ubiquitination. Journal of Molecular Recognition, 15: 3–5. doi: 10.1002/jmr.561

Author Information

  1. 1

    Institute of Environmental Health Sciences, Wayne State University, 2727 Second Avenue, Detroit, MI 48201, USA

  2. 2

    European Media Laboratory, Schloss-Wolfsbrunnenweg 33, 69118 Heidelberg, Germany

  3. 3

    European Molecular Biology Laboratory, 69012 Heidelberg, Germany

*Institute of Environmental Health Sciences, Wayne State University, 2727 Second Avenue, Detroit, MI 48201, USA

Publication History

  1. Issue published online: 18 FEB 2002
  2. Article first published online: 18 FEB 2002

Funded by

  • NIH (USPHS). Grant Number: GM59467

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Keywords:

  • ubiquitination;
  • protein degradation;
  • substrate recognition;
  • sequence motif;
  • protein domain;
  • phosphorylation

Abstract

How are proteins recognized as substrates for ubiquitination? Here we summarize insights from recent experiments that address this issue. These highlight the diversity and complexity of determinants for substrate recognition, and raise many questions for further investigation. Copyright © 2002 John Wiley & Sons, Ltd.

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