Survey of the year 2005 commercial optical biosensor literature

Authors

  • Rebecca L. Rich,

    1. Center for Biomolecular Interaction Analysis, University of Utah, Salt Lake City, UT, USA
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  • David G. Myszka

    Corresponding author
    1. Center for Biomolecular Interaction Analysis, University of Utah, Salt Lake City, UT, USA
    • Center for Biomolecular Interaction Analysis, University of Utah, School of Medicine 4A417, 50 N. Medical Drive, Salt Lake City, UT 84132, USA.
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Abstract

We identified 1113 articles (103 reviews, 1010 primary research articles) published in 2005 that describe experiments performed using commercially available optical biosensors. While this number of publications is impressive, we find that the quality of the biosensor work in these articles is often pretty poor. It is a little disappointing that there appears to be only a small set of researchers who know how to properly perform, analyze, and present biosensor data. To help focus the field, we spotlight work published by 10 research groups that exemplify the quality of data one should expect to see from a biosensor experiment. Also, in an effort to raise awareness of the common problems in the biosensor field, we provide side-by-side examples of good and bad data sets from the 2005 literature. Copyright © 2006 John Wiley & Sons, Ltd.

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