This article is a US Government work and, as such, is in the public domain in the United States of America.
Preoperative evaluation of patients awaiting liver transplantation: Comparison of multiphasic contrast-enhanced 3D magnetic resonance to helical computed tomography examinations†
Article first published online: 28 OCT 2002
Published 2002 Wiley-Liss, Inc.
Journal of Magnetic Resonance Imaging
Volume 16, Issue 5, pages 565–575, November 2002
How to Cite
Eubank, W. B., Wherry, K. L., Maki, J. H., Sahin, H., Funkhouser, C. P. and Schmiedl, U. P. (2002), Preoperative evaluation of patients awaiting liver transplantation: Comparison of multiphasic contrast-enhanced 3D magnetic resonance to helical computed tomography examinations. J. Magn. Reson. Imaging, 16: 565–575. doi: 10.1002/jmri.10194
- Issue published online: 28 OCT 2002
- Article first published online: 28 OCT 2002
- Manuscript Accepted: 7 JUN 2002
- Manuscript Received: 1 MAR 2002
- Berlex Laboratories
- magnetic resonance imaging;
- computed tomography;
- arterial anatomy
To determine the feasibility of using a multiphasic magnetic resonance (MR) examination to evaluate the hepatic arterial anatomy and parenchyma in patients awaiting orthotopic liver transplantation (OLT).
Materials and Methods
Twenty consecutive patients awaiting OLT underwent multiphasic MR (using a T1-weighted 3D gadolinium-enhanced gradient-echo (GRE) sequence and two separate injections of contrast material) and computed tomography (CT) imaging; both imaging studies were performed within a 1-week period for each patient. Quantitative and qualitative assessment of the hepatic arterial system on MR data was performed. Two independent observers classified the hepatic arterial anatomy and evaluated the hepatic parenchyma from the MR data. The prospective CT interpretation was used as the gold standard.
Overall qualitative rating of hepatic arterial system-to-background contrast on MR data was good to excellent (average pooled score of 2.00 ± 0.27), with no significant difference between the two observers after the first or second injections of contrast material. Classification of hepatic arterial anatomy by MR angiography (MRA) and CT angiography (CTA) was concordant in 85% (17/20) of patients and discordant in 15% (3/20) of patients. Focal parenchymal lesions were detected in 25% (5/20) of patients by MR and CT; however, two lesions in one patient with multiple lesions were detected only with MR.
Multiphasic T1-weighted 3D gadolinium-enhanced MR examination can provide comprehensive evaluation of the hepatic arterial anatomy and parenchyma in patients awaiting OLT. MR may offer an advantage over CT in the detection of focal parenchymal lesions. J. Magn. Reson. Imaging 2002;16:565–575. Published by Wiley-Liss, Inc.