Comparison of MR and PET imaging for the evaluation of liver metastases
Article first published online: 19 FEB 2003
Copyright © 2003 Wiley-Liss, Inc.
Journal of Magnetic Resonance Imaging
Volume 17, Issue 3, pages 343–349, March 2003
How to Cite
Yang, M., Martin, D. R., Karabulut, N. and Frick, M. P. (2003), Comparison of MR and PET imaging for the evaluation of liver metastases. J. Magn. Reson. Imaging, 17: 343–349. doi: 10.1002/jmri.10265
- Issue published online: 19 FEB 2003
- Article first published online: 19 FEB 2003
- Manuscript Accepted: 5 NOV 2002
- Manuscript Received: 6 MAY 2002
- liver lesions;
To compare the accuracy of fluoro-18-deoxyglucose positron emission tomography (FDG-PET) and dynamic-enhanced magnetic resonance imaging (MRI) scans in the diagnosis of liver metastatic lesions from colon and other sources.
Materials and Methods
Thirty consecutive patients with known or suspected metastatic lesions were scanned by both MRI and PET. Histopathology and/or clinical outcome, including cross-sectional imaging follow up, were used as a gold standard.
Of 30 patients, 16 were positive by pathology and/or clinical outcome and 14 were negative for liver metastases. The sensitivity, specificity, and positive and negative predictive values on MRI were 85.7%, 100%, 100%, and 89%, respectively, compared to 71%, 93.7%, 90.9%, and 79% on FDG-PET. The difference between the two methods was not significant (X2 = 0.2, P > 0.05).
Our study showed no significant difference in detection of liver metastases using MRI or FDG-PET. However, MRI has advantages in spatial resolution and lesion characterization. J. Magn. Reson. Imaging 2003;17:343–349. © 2003 Wiley-Liss, Inc.