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Original Research
In vivo quantification of femoral-popliteal compression during isometric thigh contraction: Assessment using MR angiography
Article first published online: 22 APR 2009
DOI: 10.1002/jmri.21700
Copyright © 2009 Wiley-Liss, Inc.
Additional Information
How to Cite
Brown, R., Nguyen, T. D., Spincemaille, P., Prince, M. R. and Wang, Y. (2009), In vivo quantification of femoral-popliteal compression during isometric thigh contraction: Assessment using MR angiography. J. Magn. Reson. Imaging, 29: 1116–1124. doi: 10.1002/jmri.21700
Publication History
- Issue published online: 22 APR 2009
- Article first published online: 22 APR 2009
- Manuscript Accepted: 2 DEC 2008
- Manuscript Received: 19 AUG 2008
Funded by
- National Institutes of Health (NIH). Grant Number: HL-060879
- Abstract
- Article
- References
- Cited By
Keywords:
- peripheral vascular disease;
- magnetic resonance imaging;
- adductor canal;
- atherosclerosis;
- vessel deformation
Abstract
Purpose
To quantify femoral-popliteal vessel deformation during thigh contraction.
Materials and Methods
Eleven subjects underwent a magnetic resonance (MR) examination of the femoral-popliteal vasculature on a 1.5 T system. A custom 3D balanced steady-state free precession (SSFP) sequence was implemented to image a 15–20-cm segment of the vasculature during relaxation and voluntary isometric thigh contraction. The arterial and venous lumina were outlined using a semiautomated method. For the artery, this outline was fit to an ellipse whose aspect ratio was used to describe arterial deformation, while venous deformation was characterized by its cross-sectional area.
Results
Focal compression of the femoral-popliteal artery during contraction was observed 94–143 mm superior to the condyle that corresponds to the distal adductor canal (AC) immediately superior to the adductor hiatus. This was illustrated by a significant reduction (P ≤ 0.05) in aspect ratio from 0.88 ± 0.06 during relaxation to 0.77 ± 0.09 during contraction. A negligible change in arterial aspect ratio was observed inferior to the AC and in the proximal AC. Similarly, venous area was dramatically reduced in the distal AC region during contraction.
Conclusion
Rapid 3D SSFP MR angiography of the femoral-popliteal vasculature during thigh contraction demonstrated focal compression of the artery in the distal AC region. This may help explain the high stent failure rate and the high likelihood of atherosclerotic disease in the AC. J. Magn. Reson. Imaging 2009;29:1116–1124. © 2009 Wiley-Liss, Inc.