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Original Research
Feasibility and reproducibility of biventricular volumetric assessment of cardiac function during exercise using real-time radial k-t SENSE magnetic resonance imaging
Article first published online: 22 APR 2009
DOI: 10.1002/jmri.21762
Copyright © 2009 Wiley-Liss, Inc.
Additional Information
How to Cite
Lurz, P., Muthurangu, V., Schievano, S., Nordmeyer, J., Bonhoeffer, P., Taylor, A. M. and Hansen, M. S. (2009), Feasibility and reproducibility of biventricular volumetric assessment of cardiac function during exercise using real-time radial k-t SENSE magnetic resonance imaging. J. Magn. Reson. Imaging, 29: 1062–1070. doi: 10.1002/jmri.21762
Publication History
- Issue published online: 22 APR 2009
- Article first published online: 22 APR 2009
- Manuscript Accepted: 2 FEB 2009
- Manuscript Received: 19 OCT 2008
Funded by
- European Union (Health-e-Child Initiative)
- British Heart Cardiovascular Initiative. Grant Number: CI/05/010
- Royal Academy of Engineering/EPSRC
- Higher Education Funding Council for England (HEFCE)
- Abstract
- Article
- References
- Cited By
Keywords:
- cardiovascular imaging;
- exercise;
- real-time imaging
Abstract
Purpose
To assess the feasibility and reproducibility of real-time radial k-t sensitivity encoding (SENSE) magnetic resonance imaging (MRI) for biventricular volumetric assessment during exercise.
Materials and Methods
In all, 12 healthy young adults underwent MRI at rest and during supine exercise at three different workload intensities. Biventricular volumes and function were assessed with 1) a radial k-t SENSE real-time sequence and 2) a scanner vendor supplied (standard) real-time sequence. Global image quality, motion fidelity, and agreement in right ventricular (RV) and left ventricular (LV) stroke volume (SV) as a surrogate measure for accuracy were assessed. Exercise MR was repeated within 1 month for assessment of reproducibility.
Results
Imaging scores were superior for radial real-time k-t SENSE images (P < 0.001). Agreement in RV and LV SV during exercise was better with radial k-t real-time (SD of difference ±3.43 vs. ±8.97 mL; P < 0.001). Agreement in cardiac output (CO) in the same subject at two different imaging sessions was better for radial k-t SENSE. This was significant for the CO calculated for the RV (SD of difference ±0.6 vs. ±0.95 L/min; P = 0.01) and LV (±0.45 vs. ±0.92 L/min; P < 0.001).
Conclusion
Radial k-t SENSE real-time imaging represents a feasible and reproducible imaging technique for biventricular assessment during exercise. J. Magn. Reson. Imaging 2009;29:1062–1070. © 2009 Wiley-Liss, Inc.