Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany
Original Research
Magnetic resonance imaging in real time: Advances using radial FLASH†
Article first published online: 24 NOV 2009
DOI: 10.1002/jmri.21987
Copyright © 2009 Wiley-Liss, Inc.
Additional Information
How to Cite
Zhang, S., Block, K. T. and Frahm, J. (2010), Magnetic resonance imaging in real time: Advances using radial FLASH. J. Magn. Reson. Imaging, 31: 101–109. doi: 10.1002/jmri.21987
- †
Publication History
- Issue published online: 20 DEC 2009
- Article first published online: 24 NOV 2009
- Manuscript Accepted: 28 SEP 2009
- Manuscript Received: 24 MAR 2009
Keywords:
- real-time MRI;
- cardiovascular MRI;
- temporomandibular joint;
- radial MRI
Abstract
Purpose
To develop technical advances for real-time magnetic resonance imaging (MRI) that allow for improved image quality and high frame rates.
Materials and Methods
The approach is based on a combination of fast low-angle shot (FLASH) MRI sequences with radial data sampling and view sharing of successive acquisitions. Gridding reconstructions provide images free from streaking or motion artifacts and with a flexible trade-off between spatial and temporal resolution. Immediate image reconstruction and online display is accomplished with the use of an unmodified 3 T MRI system. For receive coils with a large number of elements this process is supported by a user-selectable channel compression that is based on a principal component analysis and performed during initial preparation scans.
Results
In preliminary applications to healthy volunteers, real-time radial FLASH MRI visualized continuous movements of the temporomandibular joint during voluntary opening and closing of the mouth at high spatial resolution (0.75 mm in-plane) and monitored cardiac functions at high temporal resolution (20 images per second) during free breathing and without synchronization to the electrocardiogram.
Conclusion
Real-time radial FLASH MRI emerges as a simple and versatile tool for a large range of clinical applications. J. Magn. Reson. Imaging 2010. © 2009 Wiley-Liss, Inc

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