Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany
Magnetic resonance imaging in real time: Advances using radial FLASH†
Article first published online: 24 NOV 2009
Copyright © 2009 Wiley-Liss, Inc.
Journal of Magnetic Resonance Imaging
Volume 31, Issue 1, pages 101–109, January 2010
How to Cite
Zhang, S., Block, K. T. and Frahm, J. (2010), Magnetic resonance imaging in real time: Advances using radial FLASH. J. Magn. Reson. Imaging, 31: 101–109. doi: 10.1002/jmri.21987
- Issue published online: 20 DEC 2009
- Article first published online: 24 NOV 2009
- Manuscript Accepted: 28 SEP 2009
- Manuscript Received: 24 MAR 2009
- real-time MRI;
- cardiovascular MRI;
- temporomandibular joint;
- radial MRI
To develop technical advances for real-time magnetic resonance imaging (MRI) that allow for improved image quality and high frame rates.
Materials and Methods
The approach is based on a combination of fast low-angle shot (FLASH) MRI sequences with radial data sampling and view sharing of successive acquisitions. Gridding reconstructions provide images free from streaking or motion artifacts and with a flexible trade-off between spatial and temporal resolution. Immediate image reconstruction and online display is accomplished with the use of an unmodified 3 T MRI system. For receive coils with a large number of elements this process is supported by a user-selectable channel compression that is based on a principal component analysis and performed during initial preparation scans.
In preliminary applications to healthy volunteers, real-time radial FLASH MRI visualized continuous movements of the temporomandibular joint during voluntary opening and closing of the mouth at high spatial resolution (0.75 mm in-plane) and monitored cardiac functions at high temporal resolution (20 images per second) during free breathing and without synchronization to the electrocardiogram.
Real-time radial FLASH MRI emerges as a simple and versatile tool for a large range of clinical applications. J. Magn. Reson. Imaging 2010. © 2009 Wiley-Liss, Inc