The authors have no potential conflicts of interest to declare.
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Original Research
Comparison of two different injection rates of gadoxetic acid for arterial phase MRI of the liver†
Article first published online: 23 JAN 2010
DOI: 10.1002/jmri.22057
Copyright © 2010 Wiley-Liss, Inc.
Additional Information
How to Cite
Chung, S.-H., Kim, M.-J., Choi, J.-Y. and Hong, H.-S. (2010), Comparison of two different injection rates of gadoxetic acid for arterial phase MRI of the liver. J. Magn. Reson. Imaging, 31: 365–372. doi: 10.1002/jmri.22057
- †
Publication History
- Issue published online: 23 JAN 2010
- Article first published online: 23 JAN 2010
- Manuscript Accepted: 30 OCT 2009
- Manuscript Received: 2 AUG 2009
- Abstract
- Article
- References
- Cited By
Keywords:
- InjIection rate;
- Gadoxetic acid;
- Hepatic dynamic MR;
- hepatocellular carcinoma;
- contrast material
Abstract
Purpose:
To compare two different injection rates for gadoxetic acid-enhanced hepatic arterial phase images on hepatic dynamic MRI.
Materials and Methods:
Hepatic arterial phase images were obtained after an intravenous bolus injection of gadoxetic acid at a rate of 1 mL/second in 62 patients and 2 mL/second in 64 patients on a 3 Tesla MR scanner using a test-bolus injection method. The signal-to-noise ratios (SNR) of the liver, portal vein, hepatic vein, aorta, spleen and pancreas were measured. The contrast-to-noise ratio (CNR) of hypervascular hepatic tumors was calculated. Two radiologists independently scored items to evaluate image quality of hepatic arterial phase and detected hypervascular hepatocellular carcinoma (HCC).
Results:
The SNR of the aorta on the arterial phase images was significantly higher in the 1 mL/second group (235.43 ± 82.59) than in the 2 mL/second group (190.94 ± 96.90, P < 0.05). The SNRs of the liver, spleen and pancreas, the CNRs of hypervascular hepatic tumors, the detection rate of hypervascular HCC and subjective ratings for the optimal arterial enhancement were comparable between the two groups.
Conclusion:
Injection rates of 2 mL/second and 1 mL/second provided comparable image qualities on arterial phase images of hepatic dynamic MRI using gadoxetic acid. J. Magn. Reson. Imaging 2010; 31: 365–372. © 2010 Wiley-Liss, Inc.