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Technical Note
Two-point dixon technique provides robust fat suppression for multi-mouse imaging
Article first published online: 23 JAN 2010
DOI: 10.1002/jmri.22060
Copyright © 2010 Wiley-Liss, Inc.
Additional Information
How to Cite
Ragan, D. K. and Bankson, J. A. (2010), Two-point dixon technique provides robust fat suppression for multi-mouse imaging. J. Magn. Reson. Imaging, 31: 510–514. doi: 10.1002/jmri.22060
Publication History
- Issue published online: 23 JAN 2010
- Article first published online: 23 JAN 2010
- Manuscript Accepted: 20 NOV 2009
- Manuscript Received: 16 JUL 2009
- Abstract
- Article
- References
- Cited By
Keywords:
- multiple-mouse MRI;
- Dixon imaging;
- chemical saturation
Abstract
Purpose:
To determine whether Dixon-based fat separation techniques can provide more robust removal of lipid signals from multiple-mouse magnetic resonance imaging (MRI)-acquired images than conventional frequency selective chemical saturation techniques.
Materials and Methods:
A two-point Dixon technique was implemented using a RARE-based pulse sequence and techniques for multivolume fat suppression were evaluated using a 4-element array of volume resonators at 4.7 T. Images were acquired of both phantoms and mice.
Results:
Fat saturation was achieved on all four channels of the multiple mouse acquisition with the Dixon technique, while failures of fat saturation were found with chemical saturation techniques.
Conclusion:
This proof of concept study found that Dixon fat separation provided more reliable and homogenous fat suppression than chemical saturation in phantoms and in vivo. J. Magn. Reson. Imaging 2010; 31:510–514. © 2010 Wiley-Liss, Inc.