Vital signs and cognitive function are not affected by 23-sodium and 17-oxygen magnetic resonance imaging of the human brain at 9.4 T
Article first published online: 23 JUN 2010
Copyright © 2010 Wiley-Liss, Inc.
Journal of Magnetic Resonance Imaging
Volume 32, Issue 1, pages 82–87, July 2010
How to Cite
Atkinson, I. C., Sonstegaard, R., Pliskin, N. H. and Thulborn, K. R. (2010), Vital signs and cognitive function are not affected by 23-sodium and 17-oxygen magnetic resonance imaging of the human brain at 9.4 T. J. Magn. Reson. Imaging, 32: 82–87. doi: 10.1002/jmri.22221
- Issue published online: 23 JUN 2010
- Article first published online: 23 JUN 2010
- Manuscript Accepted: 6 APR 2010
- Manuscript Received: 20 JAN 2010
- University of Illinois at Chicago and the Chicago Biomedical Consortium SPARK award
- MRI safety;
- ultrahigh field MRI;
- static magnetic field;
- vital signs;
- cognitive function
To evaluate the effect of 23-sodium (23Na) and 17-oxygen (17O) magnetic resonance imaging (MRI) at 9.4 (T) on vital signs and cognitive function of the human brain.
Materials and Methods:
Vital sign and cognitive function measurements from healthy volunteers (N = 14) positioned outside and at isocenter of a 9.4 T scanner before and after 23Na and 17O MRI were compared for changes due to exposure to the static magnetic field and to the gradient switching and radiofrequency radiation during MRI.
Exposure to the 9.4 T static magnetic field and 23Na and 17O MRI at 105.92 MHz and 54.25 MHz, respectively, did not have a statistically significant (P > 0.05) effect on the vital signs or cognitive function of healthy normal adults.
23Na and 17O MRI of the human brain at 9.4 T does not have any readily demonstrated health risks reflected in vital signs or change in cognitive performance. J. Magn. Reson. Imaging 2010;32:82–87. © 2010 Wiley-Liss, Inc.