Three-dimensional contrast-enhanced hepatic MR imaging: Comparison between a centric technique and a linear approach with partial Fourier along both slice and phase directions

Authors

  • Kyung Ah Kim MD,

    1. Department of Radiology, Hallym University Sacred Heart Hospital, College of Medicine, Anyang-si, Gyeonggi-do, Korea
    2. Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
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  • Gwenael Herigault PhD,

    1. Philips Healthcare, Best, the Netherlands
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  • Myeong-Jin Kim MD,

    Corresponding author
    1. Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
    2. Institute of Gastroenterology and Brain Korea 21 project, Yonsei University College of Medicine, Seoul, Korea
    • Department of Radiology, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-752, Republic of Korea
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  • Young Eun Chung MD,

    1. Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
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  • Hye-Suk Hong MD,

    1. Department of Radiology, Hallym University Sacred Heart Hospital, College of Medicine, Anyang-si, Gyeonggi-do, Korea
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  • Sun Young Choi MD

    1. Department of Radiology, Hallym University Sacred Heart Hospital, College of Medicine, Anyang-si, Gyeonggi-do, Korea
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Abstract

Purpose

To compare the image quality of two variants of a three-dimensional (3D) gradient echo sequence (GRE) for hepatic MRI.

Materials and Methods

Thirty-nine patients underwent hepatic MRI on a 3.0 Tesla (T) magnet (Intera Achieva; Philips Medical Systems). The clinical protocol included two variants of a 3D GRE with fat suppression: (i) a “centric” approach, with elliptical centric k-space ordering and (ii) an “enhanced” approach using linear sampling and partial Fourier in both the slice and phase encoding direction. “Centric” and “Enhanced” 3D GRE images were obtained both precontrast (n = 32) and after gadoxetic acid injection (n = 39). Two reviewers jointly reviewed MR images for anatomic sharpness, overall contrast, homogeneity, and absence of artifacts. The liver-to-lesion signal difference ratio (SDR) was measured. Paired sample Wilcoxon test and paired t-tests were used.

Results

Enhanced 3D GRE images performed better than centric 3D GRE images with respect to anatomic sharpness (P = 0.0156), overall contrast (P = 0.0195), homogeneity (P < 0.0001), and absence of artifacts (P = 0.0003) on precontrast images. For postcontrast MRI, enhanced 3D GRE images showed better quality in terms of overall contrast (P = 0.0195), homogeneity (P < 0.0001), and absence of artifacts (P = 0.009). Liver-to-lesion SDR on enhanced 3D GRE images (0.48 ± 0.13) was significantly higher than that of conventional 3D GRE images (0.40 ± 0.19, P = 0.0004) on postcontrast images, but not on precontrast images.

Conclusion

The enhanced 3D GRE sequence available on our scanner provided better hepatic image quality than the centric variant, without compromising lesion contrast. J. Magn. Reson. Imaging 2011;33:160–166. © 2010 Wiley-Liss, Inc.

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