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Tandem mass spectra of ammonium adducts of monosaccharides: differentiation of diastereomers

Authors

  • K. P. Madhusudanan

    Corresponding author
    1. Sophisticated Analytical Instrument Facility, Central Drug Research Institute, Lucknow-226001, India
    • Sophisticated Analytical Instrument Facility, Central Drug Research Institute, Lucknow-226001, India.
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Abstract

Tandem mass spectra of ammonium adducts of monosaccharides gave characteristic fragmentation patterns involving elimination of NH3/H2O followed by multiple eliminations of H2O and cross ring cleavages. Tandem mass spectra were examined over a range of collision energies (1–20 eV) on a triple-quadrupole mass spectrometer. The breakdown behavior of the ammonium adducts revealed patterns that could differentiate diastereomers of monosaccharides. Copyright © 2006 John Wiley & Sons, Ltd.

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