Journal of Mass Spectrometry

Cover image for Vol. 48 Issue 2

February 2013

Volume 48, Issue 2

Pages 135–285

  1. Special feature: perspectives

    1. Top of page
    2. Special feature: perspectives
    3. Research articles
    4. Application notes
    5. Special feature: perspectives
    6. Research articles
    1. Imaging of metals in biological tissue by laser ablation inductively coupled plasma mass spectrometry (LA–ICP–MS): state of the art and future developments (page i)

      J. Sabine Becker

      Article first published online: 14 FEB 2013 | DOI: 10.1002/jms.3172

      Thumbnail image of graphical abstract

      Laser Ablation Inductively Coupled Plasma MS is one of the important inorganic mass spectrometric techniques for quite different applications in material science, environmental science and technology or geology and geochemistry. It offers a fast and precise in situ measurements of trace elements and isotope ratios with high sensitivity in solid samples. Therefore, LA-ICP-MS is often applied for bulk analysis, but pioneering work from Professor Sabine Becker's laboratory at the Research Center Juelich, Germany, has shown that LA-ICP-MS can yield valuable spatial resolved information about the distribution of trace elements in biological specimens. Metalloproteins are a large component of the human proteome and play a significant role in several disease pathways. In this month's Special Feature Prof. Becker offers a perspective on the current state and future of LA-ICP-MS for trace analysis of tissue samples, with a particular focus on applying LA-ICP-MS imaging to learn more about the role of metals in these diseases.

  2. Research articles

    1. Top of page
    2. Special feature: perspectives
    3. Research articles
    4. Application notes
    5. Special feature: perspectives
    6. Research articles
    1. Early synthetic dyes – a challenge for tandem mass spectrometry (pages 141–147)

      Katarzyna Lech, Ewa Wilicka, Janina Witowska-Jarosz and Maciej Jarosz

      Article first published online: 26 JAN 2013 | DOI: 10.1002/jms.3090

    2. Triboelectric spray ionization (pages 154–163)

      Abdil Özdemir, Jung-Lee Lin, Kent J. Gillig and Chung-Hsuan Chen

      Article first published online: 26 JAN 2013 | DOI: 10.1002/jms.3139

    3. Collision cell pressure effect on CID spectra pattern using triple quadrupole instruments: a RRKM modeling (pages 179–186)

      Farid Ichou, Denis Lesage, Xavier Machuron-Mandard, Christophe Junot, Richard B. Cole and Jean-Claude Tabet

      Article first published online: 29 JAN 2013 | DOI: 10.1002/jms.3143

    4. Liquid chromatography time-of-flight mass spectrometry evaluation of fungicides reactivity in free chlorine containing water samples (pages 216–226)

      T. Rodríguez-Cabo, M. Paganini, I. Carpinteiro, L. Fontenla, I. Rodríguez, M. C. Pietrogrande and R. Cela

      Article first published online: 3 FEB 2013 | DOI: 10.1002/jms.3151

  3. Application notes

    1. Top of page
    2. Special feature: perspectives
    3. Research articles
    4. Application notes
    5. Special feature: perspectives
    6. Research articles
  4. Special feature: perspectives

    1. Top of page
    2. Special feature: perspectives
    3. Research articles
    4. Application notes
    5. Special feature: perspectives
    6. Research articles
  5. Research articles

    1. Top of page
    2. Special feature: perspectives
    3. Research articles
    4. Application notes
    5. Special feature: perspectives
    6. Research articles
    1. Comparison of different mass spectrometry techniques in the measurement of L-[ring-13C6]phenylalanine incorporation into mixed muscle proteins (pages 269–275)

      Piotr Zabielski, G. Charles Ford, X. Mai Persson, Abdul Jaleel, Jerry D. Dewey and K. Sreekumaran Nair

      Article first published online: 3 FEB 2013 | DOI: 10.1002/jms.3120

    2. Profiling primaquine metabolites in primary human hepatocytes using UHPLC-QTOF-MS with 13C stable isotope labeling (pages 276–285)

      Bharathi Avula, Babu L. Tekwani, Narayan D. Chaurasiya, NP Dhammika Nanayakkara, Yan-Hong Wang, Shabana I. Khan, Vijender R. Adelli, Rajnish Sahu, Mahmoud A. Elsohly, James D. McChesney, Ikhlas A. Khan and Larry A. Walker

      Article first published online: 3 FEB 2013 | DOI: 10.1002/jms.3122

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