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Assessment of iatrogenic transmission of HCV in southern italy: Was the cause the salk polio vaccination?
Article first published online: 4 MAR 2003
DOI: 10.1002/jmv.10362
Copyright © 2003 Wiley-Liss, Inc.
1096-9071/asset/cover.gif?v=1&s=0dade998bc6232d09bc91c43270b9d2734a6bca3 "Journal of Medical Virology")
Additional Information
How to Cite
Montella, M., Crispo, A., Grimaldi, M., Tridente, V. and Fusco, M. (2003), Assessment of iatrogenic transmission of HCV in southern italy: Was the cause the salk polio vaccination?. J. Med. Virol., 70: 49–50. doi: 10.1002/jmv.10362
Publication History
- Issue published online: 4 MAR 2003
- Article first published online: 4 MAR 2003
- Manuscript Accepted: 2 DEC 2002
- Abstract
- References
- Cited By
Keywords:
- hepatitis C virus infection;
- parenteral Salk vaccine;
- iatrogenic transmission;
- southern Italy
Abstract
Since the first studies on hepatitis C virus (HCV) prevalence were published, it has been evident that southern Italy is an area of hyperendemicity. A recent study conducted in southern Italy suggested that the high prevalence of HCV infection might be the result of past iatrogenic transmission. Polio vaccination with the parenteral Salk vaccine between 1956 and 1965 by multiple use of unsafe glass syringes may have been one of the major causes of the spread of HCV infection among southern Italian adults who are now older than 40 years of age. Persons born between the 1940s and early 1960s have a nearly 3-fold increased risk of HCV seropositivity than the younger age group. The findings are consistent with a cohort effect of exposure to the Salk parenteral vaccination. J. Med. Virol. 70: 49–50, 2003. © 2003 Wiley-Liss, Inc.