Assessment of iatrogenic transmission of HCV in southern italy: Was the cause the salk polio vaccination?
Version of Record online: 4 MAR 2003
Copyright © 2003 Wiley-Liss, Inc.
Journal of Medical Virology
Volume 70, Issue 1, pages 49–50, May 2003
How to Cite
Montella, M., Crispo, A., Grimaldi, M., Tridente, V. and Fusco, M. (2003), Assessment of iatrogenic transmission of HCV in southern italy: Was the cause the salk polio vaccination?. J. Med. Virol., 70: 49–50. doi: 10.1002/jmv.10362
- Issue online: 4 MAR 2003
- Version of Record online: 4 MAR 2003
- Manuscript Accepted: 2 DEC 2002
- hepatitis C virus infection;
- parenteral Salk vaccine;
- iatrogenic transmission;
- southern Italy
Since the first studies on hepatitis C virus (HCV) prevalence were published, it has been evident that southern Italy is an area of hyperendemicity. A recent study conducted in southern Italy suggested that the high prevalence of HCV infection might be the result of past iatrogenic transmission. Polio vaccination with the parenteral Salk vaccine between 1956 and 1965 by multiple use of unsafe glass syringes may have been one of the major causes of the spread of HCV infection among southern Italian adults who are now older than 40 years of age. Persons born between the 1940s and early 1960s have a nearly 3-fold increased risk of HCV seropositivity than the younger age group. The findings are consistent with a cohort effect of exposure to the Salk parenteral vaccination. J. Med. Virol. 70: 49–50, 2003. © 2003 Wiley-Liss, Inc.