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Research Article
Prevalence and common genotypes of HCV infection in Sudanese patients with hepatosplenic schistosomiasis
Article first published online: 2 JUL 2007
DOI: 10.1002/jmv.20865
Copyright © 2007 Wiley-Liss, Inc.
1096-9071/asset/cover.gif?v=1&s=0dade998bc6232d09bc91c43270b9d2734a6bca3 "Journal of Medical Virology")
Additional Information
How to Cite
Mudawi, H.M.Y., Smith, H.M., Fletcher, I.A. and Fedail, S.S. (2007), Prevalence and common genotypes of HCV infection in Sudanese patients with hepatosplenic schistosomiasis. J. Med. Virol., 79: 1322–1324. doi: 10.1002/jmv.20865
Publication History
- Issue published online: 2 JUL 2007
- Article first published online: 2 JUL 2007
- Manuscript Accepted: 20 MAR 2007
- Abstract
- References
- Cited By
Keywords:
- hepatosplenic schistosomiasis;
- hepatitis C virus;
- parenteral antischistosomal therapy
Abstract
A cross-sectional hospital based study was carried out at the National Center for Gastrointestinal and Liver Disease in Khartoum, Sudan to determine the prevalence, common genotypes and risk factors for hepatitis C virus infection in Sudanese patients with hepatosplenic schistosomiasis. A total of 176 patients with hepatosplenic schistosomiasis were tested for HCV antibodies and 4.5% of the samples were reactive. PCR was positive in 2.3% of cases and genotype 4 was the major genotype isolated with subtypes 4, 4e, and 4c/4d. It is concluded that HCV was of low seroprevalence in the study population and that parenteral antischistosomal therapy was not a significant risk factor in transmission of infection in the Sudan. J. Med. Virol. 79:1322–1324, 2007. © Wiley-Liss, Inc.