The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010
Article first published online: 15 FEB 2012
Copyright © 2012 Wiley Periodicals, Inc.
Journal of Medical Virology
Volume 84, Issue 4, pages 672–678, April 2012
How to Cite
Peng, J., Kong, W., Guo, D., Liu, M., Wang, Y., Zhu, H., Pang, B., Miao, X., Yu, B., Luo, T., Hu, Q. and Zhou, D. (2012), The epidemiology and etiology of influenza-like illness in Chinese children from 2008 to 2010. J. Med. Virol., 84: 672–678. doi: 10.1002/jmv.22247
- Issue published online: 15 FEB 2012
- Article first published online: 15 FEB 2012
- Manuscript Accepted: 6 SEP 2011
- Open Research Fund Program of the State Key Laboratory of Virology of China (partial support). Grant Number: 2010007
- influenza-like illness;
- respiratory virus;
Influenza-like illness can be caused by a wide range of respiratory viruses. In order to investigate the epidemiology of viral pathogens related to influenza-like illness in children of Wuhan, the largest city in central China, throat swab samples were collected from 1,472 young patients, from July 2008 to June 2010, before and after the occurrence of the 2009 pandemic influenza A (H1N1) virus (pH1N1). It was found that 923 patients (62.7%) were positive for at least 1 virus and 90 patients (9.8%) were detected for multiple (≥2) respiratory viruses by real-time PCR detection of 16 viruses. Seasonal influenza A virus was the predominant pathogen among all the 16 viruses with a positive rate of 13.3% (196/1,472), which was followed by pH1N1 (159/1,472). It was also noted that the viral distribution pattern in Wuhan changed upon the introduction of the pH1N1 virus. J. Med. Virol. 84:672–678, 2012. © 2011 Wiley Periodicals, Inc.