Effect of gender on glucose utilization rates in healthy humans: A positron emission tomography study
Article first published online: 11 OCT 2004
Copyright © 1990 Wiley-Liss, Inc.
Journal of Neuroscience Research
Volume 27, Issue 4, pages 500–504, December 1990
How to Cite
Miura, S. A., Schapiro, M. B., Grady, C. L., Kumar, A., Salerno, J. A., Kozachuk, W. E., Wagner, E., Rapoport, S. I. and Horwitz, B. (1990), Effect of gender on glucose utilization rates in healthy humans: A positron emission tomography study. J. Neurosci. Res., 27: 500–504. doi: 10.1002/jnr.490270410
- Issue published online: 11 OCT 2004
- Article first published online: 11 OCT 2004
- Manuscript Accepted: 22 AUG 1990
- Manuscript Revised: 21 AUG 1990
- Manuscript Received: 13 JUL 1990
- Positron emission tomography;
- sex differences;
- brain metabolism
Positron emission tomography (PET) was used with 18fluorodeoxyglucose to see if gender differences in resting cerebral glucose utilization could be detected. Thirty-two healthy subjects (15 women and 17 men; age range: 21–38 yr) were examined using a high-resolution PET scanner to determine the regional cerebral metabolic rate for glucose (CMRglc) in 65 gray matter regions of interest. Whole brain CMRglc did not differ significantly between the two genders, nor did any of the regional CMRglc values. Only 1 of 65 ratios of regional-to-whole brain CMRglc differed significantly between men and women, which is consistent with chance. These results indicate that there are no differences in resting regional cerebral glucose utilization between young men and women.