This study demonstrates how the interaction between an individual's work-home segmentation preference and the perceived segmentation provided by the workplace affects work-home conflict (WHC), stress, and job satisfaction. Using a person-environment (P-E) fit theoretical base and methodology, data from 325 employees in a wide variety of occupations and organizations illustrate significant fit effects on these outcomes. Results from polynomial regression and response surface methodology highlight important asymmetric effects found in these P-E fit relationships. By demonstrating the asymmetric results of fit effects, the findings challenge previous research, which has typically advocated an integration of work and home in order to ameliorate role conflict and stress. Copyright © 2006 John Wiley & Sons, Ltd.