Adaptive bone remodeling around bonded noncemented total hip arthroplasty: A comparison between animal experiments and computer simulation

Authors

  • Dr. H. Weinans,

    Corresponding author
    1. Biomechanics Section, University of Nijmegen, Institute of Orthopedics, Nijmegen, The Netherlands
    • University of Nijmegen, Institute of Orthopedics, Biomechanics Section, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
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  • R. Huiskes,

    1. Biomechanics Section, University of Nijmegen, Institute of Orthopedics, Nijmegen, The Netherlands
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  • B. Van Rietbergen,

    1. Biomechanics Section, University of Nijmegen, Institute of Orthopedics, Nijmegen, The Netherlands
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  • D. R. Sumner,

    1. Section of Orthopedic Research, Department of Orthopedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, U.S.A.
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  • T. M. Turner,

    1. Section of Orthopedic Research, Department of Orthopedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, U.S.A.
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  • J. O. Galante

    1. Section of Orthopedic Research, Department of Orthopedic Surgery, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, U.S.A.
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Abstract

Severe loss of bone related to stress-shielding is one problem threatening the long-term integrity of noncemented total hip arthroplasty. It is widely accepted that this phenomenon is caused by adaptive bone remodeling according to Wolff's law. Recently, quantitative bone-remodeling theories have been proposed, suitable for use in computer-simulation models in combination with finite-element codes, which can be applied to simulate the long-term effect of the remodeling process. In the present paper, the results of such a computer simulation are compared with those in an animal experiment. A three-dimensional finite-element model was constructed from an animal experimental configuration concerning the implantation of a fully coated femoral hip prosthesis in dogs. The simulation results of the adaptive bone-remodeling process (geometric adaptations at the periosteal surface and density adaptations within the cancellous bone) were compared with cross-sectional measurements of the canine femurs after 2 years of follow-up. The detailed comparison showed that long-term changes in the morphology of bone around femoral components of total hip replacements can be fully explained with the present quantitative adaptive bone-remodeling theory.

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