Electronically mediated vocational assessment and guidance tools have become prominent in modern career counseling, leaving many career development professionals with questions about the nature of the computerized tools available and how to effectively apply these technologies in practice. In this article, the authors describe the general characteristics of computer-assisted career guidance systems (CACGS), review evidence of their effectiveness as compared to other career intervention modalities, briefly introduce a number of empirically supported systems, and provide practitioners with guidelines for appraising CACGS and using them successfully with clients. Recommendations address evaluation and selection of CACGS, development of appropriate strategies for incorporation of CACGS into counseling services, and matters of client education and ethical practice.