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Physics of amorphous solids

Authors

  • Lori R. Hilden,

    1. Bristol-Myers Squibb Company, P.O. Box 191, New Brunswick, New Jersey 08903-0191
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  • Kenneth R. Morris

    Corresponding author
    1. Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmacal Sciences, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907-1336
    • Department of Industrial and Physical Pharmacy, School of Pharmacy and Pharmacal Sciences, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907-1336. Telephone: 765-496-6387; Fax: 765-494-6545
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Abstract

The physical state of a dosage form, crystalline versus amorphous, is critical in determining its solid-state physical and chemical properties. This minireview describes the physics associated with the preparation and storage of amorphous solids including a review of the common theories of the glass transition and relaxation processes. © 2004 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 93:3–12, 2004

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