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Keywords:

  • Raman spectroscopy;
  • terahertz spectroscopy;
  • multivariate analysis;
  • microscopy;
  • imaging methods;
  • analysis

Abstract

This review outlines recent applications of Raman and terahertz spectroscopies within the field of pharmaceutical research. Of the two approaches, Raman is better established and more accessible, and is responsible for the majority of reviewed studies. Both techniques feature limitations, however, which are discussed in the context of methods used to circumvent apparent restrictions. Regardless, the diverse range of applications illustrates the flexibility of Raman and terahertz spectroscopies when characterizing pharmaceutical systems. © 2008 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 97:4598–4621, 2008