Relationships between the area under the first moment curve after single bolus injection and the integral of plasma concentrations after constant-rate intravenous infusion

Authors

  • Haiyung Cheng,

    Corresponding author
    1. Department of Pharmacokinetics and Drug Metabolism Merrell Dow Research Institute P.O. Box 68470 Indianapolis, IN 46268–0470
    2. Department of Pharmaceutics School of Pharmacy State University of New York at Buffalo Buffalo, NY 14260
    Current affiliation:
    1. Department of Drug Metabolism Merck Sharp & Dohme Research Laboratories West Point, PA 19486
    • Department of Pharmacokinetics and Drug Metabolism Merrell Dow Research Institute P.O. Box 68470 Indianapolis, IN 46268–0470
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  • William J. Jusko,

    1. Department of Pharmaceutics School of Pharmacy State University of New York at Buffalo Buffalo, NY 14260
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  • William R. Gillespie

    1. College of Pharmacy The University of Texas at Austin Austin, TX 78712
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