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Research Article
Optical crystallographic characteristics of some USP drugs
Article first published online: 17 SEP 2006
DOI: 10.1002/jps.2600821218
Copyright © 1993 Wiley-Liss, Inc., A Wiley Company
1520-6017/asset/cover.gif?v=1&s=e589ccf35fd012c675e943835781318cb8666bed "Journal of Pharmaceutical Sciences")
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Additional Information
How to Cite
Jordan, D. D. (1993), Optical crystallographic characteristics of some USP drugs. J. Pharm. Sci., 82: 1269–1271. doi: 10.1002/jps.2600821218
Publication History
- Issue published online: 17 SEP 2006
- Article first published online: 17 SEP 2006
- Manuscript Accepted: 25 MAR 1993
- Manuscript Received: 6 JUL 1992
Abstract
Optical crystallographic data were determined on a variety of newer USP drugs for which data had not been previously obtained. The ingredients in an unknown sample can be identified by polarized light microscopy by mounting small amounts of the material in successive specific refractive index liquids and determining refractive indices, optic sign, type of extinction, estimated 2V angle, and other optical characteristics for each ingredient present. This information can then be compared with the data listed on known drugs and excipients and all of the ingredients can be identified. To aid in the identification of unknown drugs, optical crystallographic data obtained on 52 of the newer USP drugs are presented.