Journal of Pharmaceutical Sciences

Cover image for Vol. 101 Issue 1

January 2012

Volume 101, Issue 1

Pages 1–442

  1. Commentary

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. Supersaturating drug delivery systems: Fast is not necessarily good enough (pages 7–9)

      Patrick Augustijns and Marcus E. Brewster

      Version of Record online: 23 SEP 2011 | DOI: 10.1002/jps.22750

    2. You have free access to this content
      Biowaiver monographs for immediate-release solid oral dosage forms: Stavudine (pages 10–16)

      Arthur L. L. Silva, Rodrigo Cristofoletti, Silvia Storpirtis, Varley D. Sousa, Hans E. Junginger, Vinod P. Shah, Salomon Stavchansky, Jennifer B. Dressman and Dirk M. Barends

      Version of Record online: 15 SEP 2011 | DOI: 10.1002/jps.22756

    3. Aluminum adjuvant dose guidelines in vaccine formulation for preclinical evaluations (pages 17–20)

      Simone Vecchi, Simone Bufali, David A. G. Skibinski, Derek T. O'hagan and Manmohan Singh

      Version of Record online: 14 SEP 2011 | DOI: 10.1002/jps.22759

  2. Biotechnology

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. Stability of IgG1 monoclonal antibodies in intravenous infusion bags under clinical in-use conditions (pages 21–30)

      Alavattam Sreedhara, Zephania Kwong Glover, Nicole Piros, Nina Xiao, Ankit Patel and Bruce Kabakoff

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22739

    2. Stable dry powder formulation for nasal delivery of anthrax vaccine (pages 31–47)

      Sheena H. Wang, Shaun M. Kirwan, Soman N. Abraham, Herman F. Staats and Anthony J. Hickey

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22742

    3. Downregulation of CD40 signal and induction of TGF-β by phosphatidylinositol mediates reduction in immunogenicity against recombinant human Factor VIII (pages 48–55)

      Puneet Gaitonde, Aaron Peng, Robert M. Straubinger, Richard B. Bankert and Sathy V. Balu-iyer

      Version of Record online: 23 SEP 2011 | DOI: 10.1002/jps.22746

    4. Stability of human growth hormone in supercritical carbon dioxide (pages 56–67)

      Catherine A. Kelly, Steven M. Howdle, Andrew Naylor, Graham Coxhill, Laura C. Tye, Lisbeth Illum and Andrew L. Lewis

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22747

    5. Characterization of the self-association of human interferon-α2b, albinterferon-α2b, and pegasys (pages 68–80)

      Yiming Li, Walter F. Stafford, Mark Hesselberg, David Hayes, Zhuchun Wu and Michael Byrne

      Version of Record online: 4 OCT 2011 | DOI: 10.1002/jps.22751

    6. Structure, stability, and mobility of a lyophilized IgG1 monoclonal antibody as determined using second-derivative infrared spectroscopy (pages 81–91)

      Brian M. Murphy, Ning Zhang, Robert W. Payne, Janice M. Davis, Ahmad M. Abdul-fattah, James E. Matsuura, Alan C. Herman and Mark Cornell Manning

      Version of Record online: 14 SEP 2011 | DOI: 10.1002/jps.22753

    7. Developability index: A rapid in silico tool for the screening of antibody aggregation propensity (pages 102–115)

      Timothy M. Lauer, Neeraj J. Agrawal, Naresh Chennamsetty, Kamal Egodage, Bernhard Helk and Bernhardt L. Trout

      Version of Record online: 20 SEP 2011 | DOI: 10.1002/jps.22758

  3. Drug Discovery Interface

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. Identification of novel nonsteroidal compounds as substrates or inhibitors of hASBT (pages 116–126)

      Vidula Kolhatkar, Lei Diao, Chayan Acharya, Alexander D. Mackerell Jr. and James E. Polli

      Version of Record online: 25 AUG 2011 | DOI: 10.1002/jps.22728

  4. Pharmaceutics, Preformulation and Drug Delivery

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. Effect of antioxidants and silicates on peroxides in povidone (pages 127–139)

      Ajit S. Narang, Venkatramana M. Rao and Divyakant S. Desai

      Version of Record online: 23 AUG 2011 | DOI: 10.1002/jps.22729

    2. Critical evaluation and guidance for using the coulter method for counting subvisible particles in protein solutions (pages 140–153)

      James G. Barnard, Matthew N. Rhyner and John F. Carpenter

      Version of Record online: 24 AUG 2011 | DOI: 10.1002/jps.22732

    3. Transport of the synthetic opioid peptide DADLE ([d-Ala2,d-Leu5]–Enkephalin) in neuronal cells (pages 154–163)

      Sudha Ananth, Santoshanand V. Thakkar, Jaya P. Gnana-prakasam, Pamela M. Martin, Preethi S. Ganapathy, Sylvia B. Smith and Vadivel Ganapathy

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22733

    4. Modelling transdermal drug delivery using microneedles: Effect of geometry on drug transport behaviour (pages 164–175)

      Ololade Olatunji, Diganta B. Das and Vahid Nassehi

      Version of Record online: 25 AUG 2011 | DOI: 10.1002/jps.22736

    5. A multi-technique approach to the study of structural stability and desolvation of two unusual channel hydrate solvates of finasteride (pages 176–186)

      Stephen Byard, Anuji Abraham, Paul J. T. Boulton, Robin K. Harris and Paul Hodgkinson

      Version of Record online: 9 SEP 2011 | DOI: 10.1002/jps.22740

    6. Immunogenicity of recombinant human interferon beta interacting with particles of glass, metal, and polystyrene (pages 187–199)

      Miranda M. C. Van Beers, Francesca Gilli, Huub Schellekens, Theodore W. Randolph and Wim Jiskoot

      Version of Record online: 14 SEP 2011 | DOI: 10.1002/jps.22744

    7. Supersaturation–nucleation behavior of poorly soluble drugs and its impact on the oral absorption of drugs in thermodynamically high-energy forms (pages 214–222)

      Shunsuke Ozaki, Takuma Minamisono, Taro Yamashita, Takashi Kato and Ikuo Kushida

      Version of Record online: 14 SEP 2011 | DOI: 10.1002/jps.22760

    8. Enhanced immune response against pertussis toxoid by IgA-loaded chitosan–dextran sulfate nanoparticles (pages 233–244)

      Sameer Sharma, Trilochan Ks Mukkur, Heather Ae Benson and Yan Chen

      Version of Record online: 22 SEP 2011 | DOI: 10.1002/jps.22763

    9. Transdermal delivery using a novel electrochemical device, Part 1: Device design and in vitro release/permeation of fentanyl (pages 245–255)

      Britta Schröder, Ulrich Nickel, Elisabeth Meyer and Geoffrey Lee

      Version of Record online: 23 SEP 2011 | DOI: 10.1002/jps.22765

    10. Novel pH-sensitive physical hydrogels of carboxymethyl scleroglucan (pages 256–267)

      Federica Corrente, Patrizia Paolicelli, Pietro Matricardi, Beatrice Tita, Federica Vitali and Maria Antonietta Casadei

      Version of Record online: 23 SEP 2011 | DOI: 10.1002/jps.22766

    11. Carbon–deuterium rotational-echo double-resonance NMR spectroscopy of lyophilized aspartame formulations (pages 283–290)

      Suman A. Luthra, Marcel Utz, Eric M. Gorman, Michael J. Pikal, Eric J. Munson and Joseph W. Lubach

      Version of Record online: 20 SEP 2011 | DOI: 10.1002/jps.22769

    12. Assessment of cholesterol absorption inhibitors nanostructured aluminosilicate and cholestyramine using in vitro lipolysis model (pages 291–300)

      Pavel Gershkovich, Olena Sivak, Susana Contreras-Whitney, Jerald W. Darlington and Kishor M. Wasan

      Version of Record online: 20 SEP 2011 | DOI: 10.1002/jps.22770

  5. Pharmaceutical Nanotechnology

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. Lipid nanoparticles as carrier for octyl-methoxycinnamate: in vitro percutaneous absorption and photostability studies (pages 301–311)

      Carmelo Puglia, Francesco Bonina, Luisa Rizza, Paolo Blasi, Aurelie Schoubben, Rosario Perrotta, Maria Stella Tarico and Elisabetta Damiani

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22741

  6. Pharmaceutical Techonology

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. Interdependence of drug substance physical properties and corresponding quality control strategy (pages 312–321)

      Yong Cui, Xiling Song, Mark Reynolds, KING CHUANG and Minli Xie

      Version of Record online: 14 SEP 2011 | DOI: 10.1002/jps.22754

    2. Comparison of electrospun and extruded soluplus®-based solid dosage forms of improved dissolution (pages 322–332)

      Zsombor K. Nagy, Attila Balogh, Balázs Vajna, Attila Farkas, Gergő Patyi, Áron Kramarics and György Marosi

      Version of Record online: 23 AUG 2011 | DOI: 10.1002/jps.22731

    3. Reliability evaluation of nonlinear design space in pharmaceutical product development (pages 333–341)

      Yoshihiro Hayashi, Shingo Kikuchi, Yoshinori Onuki and Kozo Takayama

      Version of Record online: 19 AUG 2011 | DOI: 10.1002/jps.22734

    4. Barrier coated drug layered particles for enhanced performance of amorphous solid dispersion dosage form (pages 342–353)

      Vibha Puri, Ajay K. Dantuluri and Arvind K. Bansal

      Version of Record online: 20 SEP 2011 | DOI: 10.1002/jps.22743

    5. Freeze-drying of nanosuspensions, part 3: Investigation of factors compromising storage stability of highly concentrated drug nanosuspensions (pages 354–362)

      Jakob Beirowski, Sabine Inghelbrecht, Albertina Arien and Henning Gieseler

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22745

  7. Pharmacokinetics, Pharmacodynamics and Drug Metabolism

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. Toxicological and toxicokinetic analysis of angiotensin (1–7) in two species (pages 373–380)

      Nicholas M. Mordwinkin, Jared R. Russell, Angela S. Burke, Gere S. Dizerega, Stan. G. Louie and Kathleen E. Rodgers

      Version of Record online: 19 AUG 2011 | DOI: 10.1002/jps.22730

    2. Contribution of organic cation transporter 3 to cisplatin cytotoxicity in human cervical cancer cells (pages 394–404)

      Qing Li, Xiujuan Peng, Hyekyung Yang, Jo-Anne Rodriguez and Yan Shu

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22752

    3. Skin microdialysis-based estimation of systemic bioavailability fraction (pages 405–413)

      Ravi Juluru, Chinmay Shukla, Hongjun Yin and Grazia Stagni

      Version of Record online: 20 SEP 2011 | DOI: 10.1002/jps.22762

  8. Notes

    1. Top of page
    2. Commentary
    3. Biotechnology
    4. Drug Discovery Interface
    5. Pharmaceutics, Preformulation and Drug Delivery
    6. Pharmaceutical Nanotechnology
    7. Pharmaceutical Techonology
    8. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    9. Notes
    1. An adsorption chromatography assay to probe bulk particle transport through hydrogels (pages 436–442)

      I. Vladescu, O. Lieleg, S. Jang and Katharina Ribbeck

      Version of Record online: 8 SEP 2011 | DOI: 10.1002/jps.22737

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