Journal of Pharmaceutical Sciences

Cover image for Vol. 101 Issue 3

March 2012

Volume 101, Issue 3

Pages 887–1335

  1. Editorial

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. Editorial (page 887)

      Ronald T. Borchardt

      Version of Record online: 14 DEC 2011 | DOI: 10.1002/jps.23021

  2. Minireview

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
  3. Reviews

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. Forced degradation of therapeutic proteins (pages 895–913)

      Andrea Hawe, Michael Wiggenhorn, Marco van de Weert, Joerg H. O. Garbe, Hanns-christian Mahler and Wim Jiskoot

      Version of Record online: 14 NOV 2011 | DOI: 10.1002/jps.22812

    2. Particles in therapeutic protein formulations, Part 1: Overview of analytical methods (pages 914–935)

      Sarah Zölls, Ruedeeporn Tantipolphan, Michael Wiggenhorn, Gerhard Winter, Wim Jiskoot, Wolfgang Friess and Andrea Hawe

      Version of Record online: 8 DEC 2011 | DOI: 10.1002/jps.23001

  4. Commentary

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. You have free access to this content
      Biowaiver monographs for immediate-release solid oral dosage forms: Primaquine phosphate (pages 936–945)

      Anita Nair, Bertil Abrahamsson, Dirk M. Barends, D. W. Groot, Sabine Kopp, James E. Polli, Vinod P. Shah and Jennifer B. Dressman

      Version of Record online: 8 DEC 2011 | DOI: 10.1002/jps.23006

    2. Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release (pages 946–954)

      Wim Jiskoot, Theodore W. Randolph, David B. Volkin, C. Russell Middaugh, Christian Schöneich, Gerhard Winter, Wolfgang Friess, Daan J. A. Crommelin and John F. Carpenter

      Version of Record online: 14 DEC 2011 | DOI: 10.1002/jps.23018

  5. Biotechnology

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. Applications of differential scanning calorimetry for thermal stability analysis of proteins: Qualification of DSC (pages 955–964)

      Jie Wen, Kelly Arthur, Letha Chemmalil, Salman Muzammil, John Gabrielson and Yijia Jiang

      Version of Record online: 6 DEC 2011 | DOI: 10.1002/jps.22820

    2. Antibody solubility behavior in monovalent salt solutions reveals specific anion effects at low ionic strength (pages 965–977)

      Le Zhang, Helming Tan, R. Matthew Fesinmeyer, Cynthia Li, David Catrone, David Le, Richard L. Remmele Jr. and Jifeng Zhang

      Version of Record online: 23 NOV 2011 | DOI: 10.1002/jps.22826

    3. Application of a ultra performance liquid chromatography method in the determination of DNA quality and stability (pages 987–997)

      Jamie Betker, Tyson Smyth, Wei Wang and Thomas J. Anchordoquy

      Version of Record online: 23 NOV 2011 | DOI: 10.1002/jps.22830

    4. Viscosity behavior of high-concentration protein mixtures (pages 1012–1020)

      William J. Galush, Lan N. Le and Jamie M. R. Moore

      Version of Record online: 13 DEC 2011 | DOI: 10.1002/jps.23002

    5. Dissolvable microneedle patches for the delivery of cell-culture-derived influenza vaccine antigens (pages 1021–1027)

      Sushma Kommareddy, Barbara C. Baudner, Seajin Oh, Sung-yun Kwon, Manmohan Singh and Derek T. O'hagan

      Version of Record online: 20 DEC 2011 | DOI: 10.1002/jps.23019

  6. Drug Discovery Interface

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. On quantitative relationships between drug-like compound lipophilicity and plasma free fraction in monkey and human (pages 1028–1039)

      Sami S. Zoghbi, Kacey B. Anderson, Kimberly J. Jenko, David A. Luckenbaugh, Robert B. Innis and Victor W. Pike

      Version of Record online: 13 DEC 2011 | DOI: 10.1002/jps.22822

  7. Pharmaceutics, Preformulation and Drug Delivery

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. Novel surface-modified nanostructured lipid carriers with partially deacetylated water-soluble chitosan for efficient ocular delivery (pages 1040–1049)

      Baocheng Tian, Qiuhua Luo, Shuangshuang Song, Dandan Liu, Hao Pan, Wenji Zhang, Ling He, Shilin Ma, Xinggang Yang and Weisan Pan

      Version of Record online: 18 NOV 2011 | DOI: 10.1002/jps.22813

    2. Influence of formulation pH and suspension state on freezing-induced agglomeration of aluminum adjuvants (pages 1050–1062)

      Maya S. Salnikova, Harrison Davis, Christopher Mensch, Lauren Celano and David S. Thiriot

      Version of Record online: 23 NOV 2011 | DOI: 10.1002/jps.22815

    3. Nanocluster budesonide formulations enhance drug delivery through endotracheal tubes (pages 1063–1072)

      Warangkana Pornputtapitak, Nashwa El-gendy and Cory Berkland

      Version of Record online: 17 NOV 2011 | DOI: 10.1002/jps.22818

    4. Pressure–temperature state diagram for the phase relationships between benfluorex hydrochloride forms I and II: A case of enantiotropic behavior (pages 1073–1078)

      Maria Barrio, Elisabetta Maccaroni, Ivo B. Rietveld, Luciana Malpezzi, Norberto Masciocchi, René Céolin and Josep-lluis Tamarit

      Version of Record online: 18 NOV 2011 | DOI: 10.1002/jps.22821

    5. Dry powder inhaler device influence on carrier particle performance (pages 1097–1107)

      Martin J. Donovan, Sin HYEN Kim, Venkatramanan Raman and Hugh D. Smyth

      Version of Record online: 17 NOV 2011 | DOI: 10.1002/jps.22824

    6. Influence of solvent on the morphology and subsequent comminution of ibuprofen crystals by air jet milling (pages 1108–1119)

      Mohammad H. Shariare, Nicholas Blagden, Marcel de Matas, Frank J. J. Leusen and Peter York

      Version of Record online: 7 DEC 2011 | DOI: 10.1002/jps.23003

    7. Formulation design and high-throughput excipient selection based on structural integrity and conformational stability of dilute and highly concentrated IgG1 monoclonal antibody solutions (pages 1120–1135)

      Akhilesh Bhambhani, Julian M. Kissmann, Sangeeta B. Joshi, David B. Volkin, Ramesh S. Kashi and C. Russell Middaugh

      Version of Record online: 6 DEC 2011 | DOI: 10.1002/jps.23008

    8. Use of ordered mesoporous silica to enhance the oral bioavailability of ezetimibe in dogs (pages 1136–1144)

      Filip Kiekens, Siemon Eelen, Loes Verheyden, Tinne Daems, Johan Martens and Guy Van Den Mooter

      Version of Record online: 20 DEC 2011 | DOI: 10.1002/jps.23016

  8. Pharmaceutical Nanotechnology

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. Effect of lipophilicity on the bioavailability of drugs after percutaneous administration by dissolving microneedles (pages 1145–1156)

      Yukako Ito, Masahiro Yoshimura, Tsutomu Tanaka and Kanji Takada

      Version of Record online: 15 NOV 2011 | DOI: 10.1002/jps.22814

    2. Benzocaine-loaded polymeric nanocapsules: Study of the anesthetic activities (pages 1157–1165)

      Nathalie Ferreira Silva De Melo, Daniele Ribeiro De Araújo, Renato Grillo, Carolina Morales Moraes, Angélica Prado De Matos, Eneida de Paula, André Henrique Rosa and Leonardo Fernandes Fraceto

      Version of Record online: 21 NOV 2011 | DOI: 10.1002/jps.22829

    3. Production and characterization of carbamazepine nanocrystals by electrospraying for continuous pharmaceutical manufacturing (pages 1178–1188)

      Mao Wang, Gregory C. Rutledge, Allan S. Myerson and Bernhardt L. Trout

      Version of Record online: 20 DEC 2011 | DOI: 10.1002/jps.23024

  9. Pharmaceutical Technology

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. Vial freeze-drying, part 1: New insights into heat transfer characteristics of tubing and molded vials (pages 1189–1201)

      Susanne Hibler, Christophe Wagner and Henning Gieseler

      Version of Record online: 7 DEC 2011 | DOI: 10.1002/jps.23004

    2. Role of excipients on solid-state properties of piroxicam during processing (pages 1202–1211)

      Niels Peter Aae Christensen, Claus Cornett and Jukka Rantanen

      Version of Record online: 9 DEC 2011 | DOI: 10.1002/jps.23014

    3. Effect of agitation regimen on the in vitro release of leuprolide from poly(lactic-co-glycolic) acid microparticles (pages 1212–1220)

      Aurélie Schoubben, Paolo Blasi and Patrick P. Deluca

      Version of Record online: 21 DEC 2011 | DOI: 10.1002/jps.23029

  10. Pharmacokinetics, Pharmacodynamics and Drug Metabolism

    1. Top of page
    2. Editorial
    3. Minireview
    4. Reviews
    5. Commentary
    6. Biotechnology
    7. Drug Discovery Interface
    8. Pharmaceutics, Preformulation and Drug Delivery
    9. Pharmaceutical Nanotechnology
    10. Pharmaceutical Technology
    11. Pharmacokinetics, Pharmacodynamics and Drug Metabolism
    1. Use of enzyme inhibitors to evaluate the conversion pathways of ester and amide prodrugs: A case study example with the prodrug ceftobiprole medocaril (pages 1242–1252)

      Gary Eichenbaum, Jennifer Skibbe, Andrew Parkinson, Mark D. Johnson, Dawn Baumgardner, Brian Ogilvie, Etsuko Usuki, Fred Tonelli, Jeff Holsapple and Anne Schmitt-Hoffmann

      Version of Record online: 17 NOV 2011 | DOI: 10.1002/jps.22816

    2. Functional consequences of genetic variations in the human organic anion transporting polypeptide 1B3 (OATP1B3) in the Korean population (pages 1302–1313)

      Yoon-Jee Chae, Kyeong-Ryoon Lee, Chi-Kyung Noh, Saeho Chong, Dae-Duk Kim, Chang-Koo Shim and Suk-Jae Chung

      Version of Record online: 6 DEC 2011 | DOI: 10.1002/jps.23005

    3. Impact of recovery on fraction unbound using equilibrium dialysis (pages 1327–1335)

      Li Di, John P. Umland, Patrick E. Trapa and Tristan S. Maurer

      Version of Record online: 9 DEC 2011 | DOI: 10.1002/jps.23013

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